MYC and therapy resistance in cancer: risks and opportunities

The MYC transcription factor, encoded by the c‐MYC proto‐oncogene, is activated by growth‐promoting signals, and is a key regulator of biosynthetic and metabolic pathways driving cell growth and proliferation. These same processes are deregulated in MYC‐driven tumors, where they become critical for...

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Bibliographic Details
Main Authors: Giulio Donati, Bruno Amati
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:Molecular Oncology
Subjects:
Online Access:https://doi.org/10.1002/1878-0261.13319