The Intriguing Relationships of von Willebrand Factor, ADAMTS13 and Cardiac Disease

The Intriguing Relationships of von Willebrand Factor, ADAMTS13 and Cardiac Disease

von Willebrand factor (VWF) is an adhesive protein involved in primary hemostasis and facilitates platelet adhesion to sites of vascular injury, thereby promoting thrombus formation. VWF exists in plasma as multimers of increasing size, with the largest (high molecular weight; HMW) expressing the gr...

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Bibliographic Details
Main Authors: Benjamin Reardon, Leonardo Pasalic, Emmanuel J. Favaloro
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
von Willebrand factor
endothelium
cardiac failure
ADAMTS13
Online Access:https://www.mdpi.com/2308-3425/8/9/115

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