Automated detection of COVID-19 through convolutional neural network using chest x-ray images

The COVID-19 epidemic has a catastrophic impact on global well-being and public health. More than 27 million confirmed cases have been reported worldwide until now. Due to the growing number of confirmed cases, and challenges to the variations of the COVID-19, timely and accurate classification of h...

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Main Authors: Rubina Sarki, Khandakar Ahmed, Hua Wang, Yanchun Zhang, Kate Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782355/?tool=EBI
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author Rubina Sarki
Khandakar Ahmed
Hua Wang
Yanchun Zhang
Kate Wang
author_facet Rubina Sarki
Khandakar Ahmed
Hua Wang
Yanchun Zhang
Kate Wang
author_sort Rubina Sarki
collection DOAJ
description The COVID-19 epidemic has a catastrophic impact on global well-being and public health. More than 27 million confirmed cases have been reported worldwide until now. Due to the growing number of confirmed cases, and challenges to the variations of the COVID-19, timely and accurate classification of healthy and infected patients is essential to control and treat COVID-19. We aim to develop a deep learning-based system for the persuasive classification and reliable detection of COVID-19 using chest radiography. Firstly, we evaluate the performance of various state-of-the-art convolutional neural networks (CNNs) proposed over recent years for medical image classification. Secondly, we develop and train CNN from scratch. In both cases, we use a public X-Ray dataset for training and validation purposes. For transfer learning, we obtain 100% accuracy for binary classification (i.e., Normal/COVID-19) and 87.50% accuracy for tertiary classification (Normal/COVID-19/Pneumonia). With the CNN trained from scratch, we achieve 93.75% accuracy for tertiary classification. In the case of transfer learning, the classification accuracy drops with the increased number of classes. The results are demonstrated by comprehensive receiver operating characteristics (ROC) and confusion metric analysis with 10-fold cross-validation.
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spelling doaj.art-2c0360866c6640598c4124b3ded0cf1d2022-12-21T19:44:31ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01171Automated detection of COVID-19 through convolutional neural network using chest x-ray imagesRubina SarkiKhandakar AhmedHua WangYanchun ZhangKate WangThe COVID-19 epidemic has a catastrophic impact on global well-being and public health. More than 27 million confirmed cases have been reported worldwide until now. Due to the growing number of confirmed cases, and challenges to the variations of the COVID-19, timely and accurate classification of healthy and infected patients is essential to control and treat COVID-19. We aim to develop a deep learning-based system for the persuasive classification and reliable detection of COVID-19 using chest radiography. Firstly, we evaluate the performance of various state-of-the-art convolutional neural networks (CNNs) proposed over recent years for medical image classification. Secondly, we develop and train CNN from scratch. In both cases, we use a public X-Ray dataset for training and validation purposes. For transfer learning, we obtain 100% accuracy for binary classification (i.e., Normal/COVID-19) and 87.50% accuracy for tertiary classification (Normal/COVID-19/Pneumonia). With the CNN trained from scratch, we achieve 93.75% accuracy for tertiary classification. In the case of transfer learning, the classification accuracy drops with the increased number of classes. The results are demonstrated by comprehensive receiver operating characteristics (ROC) and confusion metric analysis with 10-fold cross-validation.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782355/?tool=EBI
spellingShingle Rubina Sarki
Khandakar Ahmed
Hua Wang
Yanchun Zhang
Kate Wang
Automated detection of COVID-19 through convolutional neural network using chest x-ray images
PLoS ONE
title Automated detection of COVID-19 through convolutional neural network using chest x-ray images
title_full Automated detection of COVID-19 through convolutional neural network using chest x-ray images
title_fullStr Automated detection of COVID-19 through convolutional neural network using chest x-ray images
title_full_unstemmed Automated detection of COVID-19 through convolutional neural network using chest x-ray images
title_short Automated detection of COVID-19 through convolutional neural network using chest x-ray images
title_sort automated detection of covid 19 through convolutional neural network using chest x ray images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8782355/?tool=EBI
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AT huawang automateddetectionofcovid19throughconvolutionalneuralnetworkusingchestxrayimages
AT yanchunzhang automateddetectionofcovid19throughconvolutionalneuralnetworkusingchestxrayimages
AT katewang automateddetectionofcovid19throughconvolutionalneuralnetworkusingchestxrayimages