klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis
In the developing heart, blood flow transmits mechanical signals to progenitor cells that ultimately leads to valve formation. Here, the authors identify the origin of the valve progenitor cells and fibronectin1bas a transcriptional target of the mechanotransduced signals responsible for valve forma...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2016-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms11646 |
| _version_ | 1819195798048473088 |
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| author | Emily Steed Nathalie Faggianelli Stéphane Roth Caroline Ramspacher Jean-Paul Concordet Julien Vermot |
| author_facet | Emily Steed Nathalie Faggianelli Stéphane Roth Caroline Ramspacher Jean-Paul Concordet Julien Vermot |
| author_sort | Emily Steed |
| collection | DOAJ |
| description | In the developing heart, blood flow transmits mechanical signals to progenitor cells that ultimately leads to valve formation. Here, the authors identify the origin of the valve progenitor cells and fibronectin1bas a transcriptional target of the mechanotransduced signals responsible for valve formation. |
| first_indexed | 2024-12-23T02:18:29Z |
| format | Article |
| id | doaj.art-2c0831bd19cb4f7abaf7a6a2a2d5adbc |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-23T02:18:29Z |
| publishDate | 2016-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-2c0831bd19cb4f7abaf7a6a2a2d5adbc2022-12-21T18:03:36ZengNature PortfolioNature Communications2041-17232016-05-017111410.1038/ncomms11646klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesisEmily Steed0Nathalie Faggianelli1Stéphane Roth2Caroline Ramspacher3Jean-Paul Concordet4Julien Vermot5Institut de Génétique et de Biologie Moléculaire et CellulaireInstitut de Génétique et de Biologie Moléculaire et CellulaireInstitut de Génétique et de Biologie Moléculaire et CellulaireInstitut de Génétique et de Biologie Moléculaire et CellulaireMuséum National d'Histoire NaturelleInstitut de Génétique et de Biologie Moléculaire et CellulaireIn the developing heart, blood flow transmits mechanical signals to progenitor cells that ultimately leads to valve formation. Here, the authors identify the origin of the valve progenitor cells and fibronectin1bas a transcriptional target of the mechanotransduced signals responsible for valve formation.https://doi.org/10.1038/ncomms11646 |
| spellingShingle | Emily Steed Nathalie Faggianelli Stéphane Roth Caroline Ramspacher Jean-Paul Concordet Julien Vermot klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis Nature Communications |
| title | klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis |
| title_full | klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis |
| title_fullStr | klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis |
| title_full_unstemmed | klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis |
| title_short | klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis |
| title_sort | klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis |
| url | https://doi.org/10.1038/ncomms11646 |
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