The Impact of Vitamin D and Its Dietary Supplementation in Breast Cancer Prevention: An Integrative Review
Vitamin D deficiency is currently a significant public health issue closely linked to numerous diseases, such as breast cancer. This study aims to determine the estimated optimal serum levels of vitamin D to have a protective effect against breast cancer, in addition to exploring the biological mech...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/16/5/573 |
| _version_ | 1797264071671676928 |
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| author | Antía Torres Carla Cameselle Paz Otero Jesus Simal-Gandara |
| author_facet | Antía Torres Carla Cameselle Paz Otero Jesus Simal-Gandara |
| author_sort | Antía Torres |
| collection | DOAJ |
| description | Vitamin D deficiency is currently a significant public health issue closely linked to numerous diseases, such as breast cancer. This study aims to determine the estimated optimal serum levels of vitamin D to have a protective effect against breast cancer, in addition to exploring the biological mechanisms and risk factors involved. A literature search of articles published in the last 5 years was conducted, and simple statistical analyses using mean and standard deviation were performed to calculate the average concentration of vitamin D from different available studies. It has been observed that serum levels of vitamin D ≥ 40.26 ng/mL ± 14.19 ng/mL could exert a protective effect against breast cancer. Additionally, various biological mechanisms, such as those related to the immune system, and risk factors like diet implicated in this relationship were elucidated. Consequently, it can be concluded that proper serum levels of vitamin D may have a protective effect against breast cancer, and dietary supplementation may be an appropriate procedure to achieve these optimal vitamin D concentrations. |
| first_indexed | 2024-04-25T00:23:04Z |
| format | Article |
| id | doaj.art-2c0899070b1641978e485694ccc9831a |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-04-25T00:23:04Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-2c0899070b1641978e485694ccc9831a2024-03-12T16:51:46ZengMDPI AGNutrients2072-66432024-02-0116557310.3390/nu16050573The Impact of Vitamin D and Its Dietary Supplementation in Breast Cancer Prevention: An Integrative ReviewAntía Torres0Carla Cameselle1Paz Otero2Jesus Simal-Gandara3Nutrition and Bromatology Group, Department of Analytical Chemistry and Food Science, Faculty of Science, University de Vigo, E-32004 Ourense, SpainNutrition and Bromatology Group, Department of Analytical Chemistry and Food Science, Faculty of Science, University de Vigo, E-32004 Ourense, SpainNutrition and Bromatology Group, Department of Analytical Chemistry and Food Science, Faculty of Science, University de Vigo, E-32004 Ourense, SpainNutrition and Bromatology Group, Department of Analytical Chemistry and Food Science, Faculty of Science, University de Vigo, E-32004 Ourense, SpainVitamin D deficiency is currently a significant public health issue closely linked to numerous diseases, such as breast cancer. This study aims to determine the estimated optimal serum levels of vitamin D to have a protective effect against breast cancer, in addition to exploring the biological mechanisms and risk factors involved. A literature search of articles published in the last 5 years was conducted, and simple statistical analyses using mean and standard deviation were performed to calculate the average concentration of vitamin D from different available studies. It has been observed that serum levels of vitamin D ≥ 40.26 ng/mL ± 14.19 ng/mL could exert a protective effect against breast cancer. Additionally, various biological mechanisms, such as those related to the immune system, and risk factors like diet implicated in this relationship were elucidated. Consequently, it can be concluded that proper serum levels of vitamin D may have a protective effect against breast cancer, and dietary supplementation may be an appropriate procedure to achieve these optimal vitamin D concentrations.https://www.mdpi.com/2072-6643/16/5/573vitamin Dbreast cancerpreventionoptimal levelsmechanism of actionrisk factors |
| spellingShingle | Antía Torres Carla Cameselle Paz Otero Jesus Simal-Gandara The Impact of Vitamin D and Its Dietary Supplementation in Breast Cancer Prevention: An Integrative Review Nutrients vitamin D breast cancer prevention optimal levels mechanism of action risk factors |
| title | The Impact of Vitamin D and Its Dietary Supplementation in Breast Cancer Prevention: An Integrative Review |
| title_full | The Impact of Vitamin D and Its Dietary Supplementation in Breast Cancer Prevention: An Integrative Review |
| title_fullStr | The Impact of Vitamin D and Its Dietary Supplementation in Breast Cancer Prevention: An Integrative Review |
| title_full_unstemmed | The Impact of Vitamin D and Its Dietary Supplementation in Breast Cancer Prevention: An Integrative Review |
| title_short | The Impact of Vitamin D and Its Dietary Supplementation in Breast Cancer Prevention: An Integrative Review |
| title_sort | impact of vitamin d and its dietary supplementation in breast cancer prevention an integrative review |
| topic | vitamin D breast cancer prevention optimal levels mechanism of action risk factors |
| url | https://www.mdpi.com/2072-6643/16/5/573 |
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