Effects of Marijuana Use in Patients Undergoing Abdominal Free Flap Breast Reconstruction
Background:. Marijuana use has been associated with vascular inflammation and clotting, resulting in endothelial damage and arteritis. As marijuana use rises in the United States, few studies have evaluated its impact on surgical outcomes and wound healing in free flap breast reconstruction. Methods...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer
2024-03-01
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| Series: | Plastic and Reconstructive Surgery, Global Open |
| Online Access: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000005657 |
| _version_ | 1797243073717075968 |
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| author | Tala Al-Saghir, BS Alexander Vraa, MBBS Kinan Sawar, BS Gordon Jacobsen, MS Maristella S. Evangelista, MD Dunya Atisha, MD |
| author_facet | Tala Al-Saghir, BS Alexander Vraa, MBBS Kinan Sawar, BS Gordon Jacobsen, MS Maristella S. Evangelista, MD Dunya Atisha, MD |
| author_sort | Tala Al-Saghir, BS |
| collection | DOAJ |
| description | Background:. Marijuana use has been associated with vascular inflammation and clotting, resulting in endothelial damage and arteritis. As marijuana use rises in the United States, few studies have evaluated its impact on surgical outcomes and wound healing in free flap breast reconstruction.
Methods:. A retrospective cohort study of patients undergoing abdominal free flap breast reconstruction between 2016 and 2022 at a large metropolitan healthcare system was performed. Patient demographics, comorbidities, procedural details, and complications were analyzed. Minor complications were defined as skin or fat necrosis not requiring intervention, nipple loss, any wound requiring management in the clinic, hematoma, and seroma. Major complications were defined as reoperation, flap loss, cardiac or thromboembolic events, and hospital readmission. Active marijuana users were those with marijuana use within 12 weeks of surgery.
Results:. In total, 168 patients underwent 276 deep inferior epigastric artery-based flaps for breast reconstruction. There were 21 active marijuana users. There were no significant differences in patient demographics, cancer treatment, or minor and major complications. However, there were higher rates of active nicotine use (P = 0.001) and anxiety/depression amongst active marijuana users (P = 0.002). Active users had higher rates of bilateral breast reconstruction (P = 0.029), but no significant differences in other operative details.
Conclusions:. Active marijuana use of unknown frequency may be safe in patients undergoing breast free flap reconstruction. Advising marijuana abstinence preoperatively may not alter patient outcomes. Further studies of greater sample size are needed to evaluate marijuana’s impact on outcomes associated with breast reconstruction using free flap. |
| first_indexed | 2024-04-24T18:49:19Z |
| format | Article |
| id | doaj.art-2c0a283a75a94f0685705145a48c401a |
| institution | Directory Open Access Journal |
| issn | 2169-7574 |
| language | English |
| last_indexed | 2024-04-24T18:49:19Z |
| publishDate | 2024-03-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Plastic and Reconstructive Surgery, Global Open |
| spelling | doaj.art-2c0a283a75a94f0685705145a48c401a2024-03-27T03:41:49ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742024-03-01123e565710.1097/GOX.0000000000005657202403000-00009Effects of Marijuana Use in Patients Undergoing Abdominal Free Flap Breast ReconstructionTala Al-Saghir, BS0Alexander Vraa, MBBS1Kinan Sawar, BS2Gordon Jacobsen, MS3Maristella S. Evangelista, MD4Dunya Atisha, MD5From the * Wayne State University School of Medicine, Detroit, Mich† Department of General Surgery, Henry Ford Hospital, Detroit, Mich.From the * Wayne State University School of Medicine, Detroit, Mich‡ Department of Public Health Sciences, Henry Ford Hospital, Detroit, Mich.§ Department of Plastic Surgery, Henry Ford Hospital, Detroit, Mich.§ Department of Plastic Surgery, Henry Ford Hospital, Detroit, Mich.Background:. Marijuana use has been associated with vascular inflammation and clotting, resulting in endothelial damage and arteritis. As marijuana use rises in the United States, few studies have evaluated its impact on surgical outcomes and wound healing in free flap breast reconstruction. Methods:. A retrospective cohort study of patients undergoing abdominal free flap breast reconstruction between 2016 and 2022 at a large metropolitan healthcare system was performed. Patient demographics, comorbidities, procedural details, and complications were analyzed. Minor complications were defined as skin or fat necrosis not requiring intervention, nipple loss, any wound requiring management in the clinic, hematoma, and seroma. Major complications were defined as reoperation, flap loss, cardiac or thromboembolic events, and hospital readmission. Active marijuana users were those with marijuana use within 12 weeks of surgery. Results:. In total, 168 patients underwent 276 deep inferior epigastric artery-based flaps for breast reconstruction. There were 21 active marijuana users. There were no significant differences in patient demographics, cancer treatment, or minor and major complications. However, there were higher rates of active nicotine use (P = 0.001) and anxiety/depression amongst active marijuana users (P = 0.002). Active users had higher rates of bilateral breast reconstruction (P = 0.029), but no significant differences in other operative details. Conclusions:. Active marijuana use of unknown frequency may be safe in patients undergoing breast free flap reconstruction. Advising marijuana abstinence preoperatively may not alter patient outcomes. Further studies of greater sample size are needed to evaluate marijuana’s impact on outcomes associated with breast reconstruction using free flap.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000005657 |
| spellingShingle | Tala Al-Saghir, BS Alexander Vraa, MBBS Kinan Sawar, BS Gordon Jacobsen, MS Maristella S. Evangelista, MD Dunya Atisha, MD Effects of Marijuana Use in Patients Undergoing Abdominal Free Flap Breast Reconstruction Plastic and Reconstructive Surgery, Global Open |
| title | Effects of Marijuana Use in Patients Undergoing Abdominal Free Flap Breast Reconstruction |
| title_full | Effects of Marijuana Use in Patients Undergoing Abdominal Free Flap Breast Reconstruction |
| title_fullStr | Effects of Marijuana Use in Patients Undergoing Abdominal Free Flap Breast Reconstruction |
| title_full_unstemmed | Effects of Marijuana Use in Patients Undergoing Abdominal Free Flap Breast Reconstruction |
| title_short | Effects of Marijuana Use in Patients Undergoing Abdominal Free Flap Breast Reconstruction |
| title_sort | effects of marijuana use in patients undergoing abdominal free flap breast reconstruction |
| url | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000005657 |
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