Defining the role of Lgr5+ stem cells in colorectal cancer: from basic research to clinical applications
Editorial summary Intestinal epithelium is structured by two distinct components: the villi and the crypts. The crypts harbor stem cells expressing Lgr5 and thus have been a representative model to study tissue stem cell functions. Recent advances in organoid technology and analytical modalities hav...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-07-01
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| Series: | Genome Medicine |
| Online Access: | http://link.springer.com/article/10.1186/s13073-017-0460-y |