Copper-Catalyzed Difluoroalkylation Reaction

Copper-Catalyzed Difluoroalkylation Reaction

This review describes recent advances in copper-catalyzed difluoroalkylation reactions. The RCF<sub>2</sub> radical is generally proposed in the mechanism of these reactions. At present, various types of copper-catalyzed difluoroalkylation reactions have been realized. According to their...

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Bibliographic Details
Main Authors: Dao-Qing Dong, Shao-Hui Yang, Pei Wu, Jin-Zhi Wang, Ling-Hao Min, Hao Yang, Meng-Yu Zhou, Ze-Hui Wei, Cai-Zhen Ding, Yan-Li Wang, Jia-Hui Gao, Shu-Jie Wang, Zu-Li Wang
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
difluoroalkylation
copper
radical
cyclization
multicomponent
coupling reaction
Online Access:https://www.mdpi.com/1420-3049/27/23/8461
Description
Summary:This review describes recent advances in copper-catalyzed difluoroalkylation reactions. The RCF<sub>2</sub> radical is generally proposed in the mechanism of these reactions. At present, various types of copper-catalyzed difluoroalkylation reactions have been realized. According to their characteristics, we classify these difluoroalkylation reactions into three types.
ISSN:1420-3049

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