stAPAminer: Mining Spatial Patterns of Alternative Polyadenylation for Spatially Resolved Transcriptomic Studies

stAPAminer: Mining Spatial Patterns of Alternative Polyadenylation for Spatially Resolved Transcriptomic Studies

Alternative polyadenylation (APA) contributes to transcriptome complexity and gene expression regulation and has been implicated in various cellular processes and diseases. Single-cell RNA sequencing (scRNA-seq) has enabled the profiling of APA at the single-cell level; however, the spatial informat...

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Bibliographic Details
Main Authors: Guoli Ji, Qi Tang, Sheng Zhu, Junyi Zhu, Pengchao Ye, Shuting Xia, Xiaohui Wu
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
Alternative polyadenylation
Spatial transcriptomics
Single-cell RNA sequencing
Spatial pattern
Imputation
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022923000037

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