Assessment of quality of life before and after successful percutaneous transvenous mitral commissurotomy in patients with severe mitral stenosis

Background: Rheumatic mitral stenosis (MS) is a significant cause of morbidity and mortality in India. Percutaneous transvenous mitral commissurotomy (PTMC) has become the procedure of choice for severe MS with pliable leaflets. Despite a wealth of literature on the technical aspects of PTMC, there...

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Main Authors: Prashant Bhardwaj, Suprakash Chaudhury, Aradhana Aneja, Vinay Jetley, Tejvir Singh Walia, Swaleha Mujawar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Industrial Psychiatry Journal
Subjects:
Online Access:http://www.industrialpsychiatry.org/article.asp?issn=0972-6748;year=2019;volume=28;issue=1;spage=51;epage=57;aulast=Bhardwaj
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author Prashant Bhardwaj
Suprakash Chaudhury
Aradhana Aneja
Vinay Jetley
Tejvir Singh Walia
Swaleha Mujawar
author_facet Prashant Bhardwaj
Suprakash Chaudhury
Aradhana Aneja
Vinay Jetley
Tejvir Singh Walia
Swaleha Mujawar
author_sort Prashant Bhardwaj
collection DOAJ
description Background: Rheumatic mitral stenosis (MS) is a significant cause of morbidity and mortality in India. Percutaneous transvenous mitral commissurotomy (PTMC) has become the procedure of choice for severe MS with pliable leaflets. Despite a wealth of literature on the technical aspects of PTMC, there is a dearth of literature addressing the impact of PTMC on the quality of life (QOL). Aim: The aim of the study is to assess the impact of PTMC on clinical status and QOL of patients with severe MS. Materials and Methods: Twenty-five consecutive patients with severe MS undergoing PTMC were included in the study with their informed consent. All patients were subjected to routine blood tests, electrocardiogram, chest X-ray, two-dimensional and color echocardiography, treadmill test (TMT), and World Health Organization (WHO) QOL scale. The echocardiography, TMT, and WHOQOL scale were repeated after the procedure. Results: The procedural success was 98%. The mean (range) mitral valve area preprocedure was 0.82 (0.59–0.92) cm2 and postprocedure was 1.61 (1.51–1.76) cm2. The difference was statistically significant (t = 5.02; P < 0.01). The mean (range) of TMT preprocedure was 4.05 (3.0–7.0) METS and postprocedure was 8.52 (6–12) METS. The difference was statistically significant (T = 3.08; P < 0.01). The mean (range) of QOL assessment pre- and post-procedure on physical domain was 8.83 (8.3–10.1) which increased to 11.11 (10–12.7); on social relationship domain from 9.17 (7.5–12.4) to 11.37 (9.4–12.0); on personal relationship from 11.6 (11–13) to 12.52 (12–13); on environment domain from 10.78 (10.2–11.7) to 11.56 (10.8–12); and on level of independence from 9.02 (8–10) to 12.29 (11.0–13.6). All the differences were statistically significant (Wilcoxon signed-rank test z = −4.376; −4.379; −4.234; −4.200; −4.375; respectively, all P < 0.001 highly significant). Conclusions: PTMC resulted in a significant improvement in the QOL of patients with severe MS. The significant improvement in QOL post-PTMC may be an indication for offering PTMC at an earlier stage to those patients whose QOL is severely compromised.
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spelling doaj.art-2c176f9c56c246aaa8d36ff766001fa42022-12-22T03:42:02ZengWolters Kluwer Medknow PublicationsIndustrial Psychiatry Journal0972-67480976-27952019-01-01281515710.4103/ipj.ipj_4_19Assessment of quality of life before and after successful percutaneous transvenous mitral commissurotomy in patients with severe mitral stenosisPrashant BhardwajSuprakash ChaudhuryAradhana AnejaVinay JetleyTejvir Singh WaliaSwaleha MujawarBackground: Rheumatic mitral stenosis (MS) is a significant cause of morbidity and mortality in India. Percutaneous transvenous mitral commissurotomy (PTMC) has become the procedure of choice for severe MS with pliable leaflets. Despite a wealth of literature on the technical aspects of PTMC, there is a dearth of literature addressing the impact of PTMC on the quality of life (QOL). Aim: The aim of the study is to assess the impact of PTMC on clinical status and QOL of patients with severe MS. Materials and Methods: Twenty-five consecutive patients with severe MS undergoing PTMC were included in the study with their informed consent. All patients were subjected to routine blood tests, electrocardiogram, chest X-ray, two-dimensional and color echocardiography, treadmill test (TMT), and World Health Organization (WHO) QOL scale. The echocardiography, TMT, and WHOQOL scale were repeated after the procedure. Results: The procedural success was 98%. The mean (range) mitral valve area preprocedure was 0.82 (0.59–0.92) cm2 and postprocedure was 1.61 (1.51–1.76) cm2. The difference was statistically significant (t = 5.02; P < 0.01). The mean (range) of TMT preprocedure was 4.05 (3.0–7.0) METS and postprocedure was 8.52 (6–12) METS. The difference was statistically significant (T = 3.08; P < 0.01). The mean (range) of QOL assessment pre- and post-procedure on physical domain was 8.83 (8.3–10.1) which increased to 11.11 (10–12.7); on social relationship domain from 9.17 (7.5–12.4) to 11.37 (9.4–12.0); on personal relationship from 11.6 (11–13) to 12.52 (12–13); on environment domain from 10.78 (10.2–11.7) to 11.56 (10.8–12); and on level of independence from 9.02 (8–10) to 12.29 (11.0–13.6). All the differences were statistically significant (Wilcoxon signed-rank test z = −4.376; −4.379; −4.234; −4.200; −4.375; respectively, all P < 0.001 highly significant). Conclusions: PTMC resulted in a significant improvement in the QOL of patients with severe MS. The significant improvement in QOL post-PTMC may be an indication for offering PTMC at an earlier stage to those patients whose QOL is severely compromised.http://www.industrialpsychiatry.org/article.asp?issn=0972-6748;year=2019;volume=28;issue=1;spage=51;epage=57;aulast=Bhardwajmitral stenosispercutaneous transvenous mitral commissurotomyquality of life
spellingShingle Prashant Bhardwaj
Suprakash Chaudhury
Aradhana Aneja
Vinay Jetley
Tejvir Singh Walia
Swaleha Mujawar
Assessment of quality of life before and after successful percutaneous transvenous mitral commissurotomy in patients with severe mitral stenosis
Industrial Psychiatry Journal
mitral stenosis
percutaneous transvenous mitral commissurotomy
quality of life
title Assessment of quality of life before and after successful percutaneous transvenous mitral commissurotomy in patients with severe mitral stenosis
title_full Assessment of quality of life before and after successful percutaneous transvenous mitral commissurotomy in patients with severe mitral stenosis
title_fullStr Assessment of quality of life before and after successful percutaneous transvenous mitral commissurotomy in patients with severe mitral stenosis
title_full_unstemmed Assessment of quality of life before and after successful percutaneous transvenous mitral commissurotomy in patients with severe mitral stenosis
title_short Assessment of quality of life before and after successful percutaneous transvenous mitral commissurotomy in patients with severe mitral stenosis
title_sort assessment of quality of life before and after successful percutaneous transvenous mitral commissurotomy in patients with severe mitral stenosis
topic mitral stenosis
percutaneous transvenous mitral commissurotomy
quality of life
url http://www.industrialpsychiatry.org/article.asp?issn=0972-6748;year=2019;volume=28;issue=1;spage=51;epage=57;aulast=Bhardwaj
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