NEIL1 drives the initiation of colorectal cancer through transcriptional regulation of COL17A1

Summary: Deficiency of DNA repair pathways drives the development of colorectal cancer. However, the role of the base excision repair (BER) pathway in colorectal cancer initiation remains unclear. This study shows that Nei-like DNA glycosylase 1 (NEIL1) is highly expressed in colorectal cancer (CRC)...

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Bibliographic Details
Main Authors: Jing-Hua Cao, Chen-Hui Cao, Jin-Long Lin, Si-Yu Li, Long-Jun He, Kai Han, Jie-Wei Chen, Si Li, Xin Wang, Dan Xie, Feng-Wei Wang
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723016650