Enteric glial cells aggravate the intestinal epithelial barrier damage by secreting S100β under high-altitude conditions

Enteric glial cells aggravate the intestinal epithelial barrier damage by secreting S100β under high-altitude conditions

Abstract Damage to the intestinal epithelial barrier (IEB) has been reported under high-altitude (HA) conditions and may be responsible for HA-associated gastrointestinal (GI) disorders. However, this pathogenetic mechanism does not fully explain the GI stress symptoms, such as flatulence and motili...

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Bibliographic Details
Main Authors: Huichao Xie, Xiong Zeng, Wensheng Wang, Wei Wang, Ben Han, QianShan Tan, Qiu Hu, Xingyu Liu, Shuaishuai Chen, Jun Chen, Lihua Sun, Yihui Chen, Weidong Xiao
Format: Article
Language:English
Published: Springer 2023-10-01
Series:Molecular Biomedicine
Subjects:
High-altitude
Hypoxia
Enteric glial cells
S100β
Intestinal epithelial barrier
Online Access:https://doi.org/10.1186/s43556-023-00143-1

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