Microfluidic devices for light stimulation of cell suspensions: experimental analysis of the flow behaviour using a micro-PIV system

Photobiomodulation, the light stimulation of regenerative active cells, offers great potential for promoting tissue repair and regeneration. In this study, we show the design and fabrication of two microchannel devices for light stimulation of cell suspensions. The microchannels in the 3D-printed de...

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Bibliographic Details
Main Authors: Thürling Mario, Verena Witt Anna, Mau Robert, Drobek Christoph, Seitz Hermann
Format: Article
Language:English
Published: De Gruyter 2023-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2023-1021
Description
Summary:Photobiomodulation, the light stimulation of regenerative active cells, offers great potential for promoting tissue repair and regeneration. In this study, we show the design and fabrication of two microchannel devices for light stimulation of cell suspensions. The microchannels in the 3D-printed devices allow the uniform distribution of cells and exposure to light. Our experimental results demonstrate the ability of these microfluidic devices to improve light intake of cells in suspensions during photobiomodulation, thus enhancing the therapeutic potential.
ISSN:2364-5504