Microfluidic devices for light stimulation of cell suspensions: experimental analysis of the flow behaviour using a micro-PIV system
Photobiomodulation, the light stimulation of regenerative active cells, offers great potential for promoting tissue repair and regeneration. In this study, we show the design and fabrication of two microchannel devices for light stimulation of cell suspensions. The microchannels in the 3D-printed de...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2023-09-01
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| Series: | Current Directions in Biomedical Engineering |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/cdbme-2023-1021 |
| _version_ | 1797646355399704576 |
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| author | Thürling Mario Verena Witt Anna Mau Robert Drobek Christoph Seitz Hermann |
| author_facet | Thürling Mario Verena Witt Anna Mau Robert Drobek Christoph Seitz Hermann |
| author_sort | Thürling Mario |
| collection | DOAJ |
| description | Photobiomodulation, the light stimulation of regenerative active cells, offers great potential for promoting tissue repair and regeneration. In this study, we show the design and fabrication of two microchannel devices for light stimulation of cell suspensions. The microchannels in the 3D-printed devices allow the uniform distribution of cells and exposure to light. Our experimental results demonstrate the ability of these microfluidic devices to improve light intake of cells in suspensions during photobiomodulation, thus enhancing the therapeutic potential. |
| first_indexed | 2024-03-11T15:00:33Z |
| format | Article |
| id | doaj.art-2c1ca4ef264846bb8395ae78c8426981 |
| institution | Directory Open Access Journal |
| issn | 2364-5504 |
| language | English |
| last_indexed | 2024-03-11T15:00:33Z |
| publishDate | 2023-09-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Current Directions in Biomedical Engineering |
| spelling | doaj.art-2c1ca4ef264846bb8395ae78c84269812023-10-30T07:58:11ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042023-09-0191818410.1515/cdbme-2023-1021Microfluidic devices for light stimulation of cell suspensions: experimental analysis of the flow behaviour using a micro-PIV systemThürling Mario0Verena Witt Anna1Mau Robert2Drobek Christoph3Seitz Hermann4Microfluidics, Faculty of Mechanical Engineering and Marine Technology, University of Rostock, Justus-von-Liebig Weg 6, 18059Rostock, GermanyMicrofluidics, Faculty of Mechanical Engineering and Marine Technology, University of Rostock, Justus-von-Liebig Weg 6, 18059Rostock, GermanyMicrofluidics, Faculty of Mechanical Engineering and Marine Technology, University of Rostock, Justus-von-Liebig Weg 6, 18059Rostock, GermanyMicrofluidics, Faculty of Mechanical Engineering and Marine Technology, University of Rostock, Justus-von-Liebig Weg 6, 18059Rostock, GermanyMicrofluidics, Faculty of Mechanical Engineering and Marine Technology, University of Rostock, Justus-von-Liebig Weg 6, 18059Rostock, GermanyPhotobiomodulation, the light stimulation of regenerative active cells, offers great potential for promoting tissue repair and regeneration. In this study, we show the design and fabrication of two microchannel devices for light stimulation of cell suspensions. The microchannels in the 3D-printed devices allow the uniform distribution of cells and exposure to light. Our experimental results demonstrate the ability of these microfluidic devices to improve light intake of cells in suspensions during photobiomodulation, thus enhancing the therapeutic potential.https://doi.org/10.1515/cdbme-2023-1021microfluidic devicelight stimulationcell suspension3d-printingmicro-piv |
| spellingShingle | Thürling Mario Verena Witt Anna Mau Robert Drobek Christoph Seitz Hermann Microfluidic devices for light stimulation of cell suspensions: experimental analysis of the flow behaviour using a micro-PIV system Current Directions in Biomedical Engineering microfluidic device light stimulation cell suspension 3d-printing micro-piv |
| title | Microfluidic devices for light stimulation of cell suspensions: experimental analysis of the flow behaviour using a micro-PIV system |
| title_full | Microfluidic devices for light stimulation of cell suspensions: experimental analysis of the flow behaviour using a micro-PIV system |
| title_fullStr | Microfluidic devices for light stimulation of cell suspensions: experimental analysis of the flow behaviour using a micro-PIV system |
| title_full_unstemmed | Microfluidic devices for light stimulation of cell suspensions: experimental analysis of the flow behaviour using a micro-PIV system |
| title_short | Microfluidic devices for light stimulation of cell suspensions: experimental analysis of the flow behaviour using a micro-PIV system |
| title_sort | microfluidic devices for light stimulation of cell suspensions experimental analysis of the flow behaviour using a micro piv system |
| topic | microfluidic device light stimulation cell suspension 3d-printing micro-piv |
| url | https://doi.org/10.1515/cdbme-2023-1021 |
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