Knowledge, Attitude, and Practice of Metformin Extended-Release Tablets Among Clinicians in China: A Cross-Sectional Survey

Background: Metformin extended-release (XR) is a once-daily alternative conventional immediate-release (IR) tablet for adults with type 2 diabetes.Aim: This study aimed to investigate the knowledge, attitude, and practice of the use of metformin XR tablets among clinicians.Methods: We conducted a cr...

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Main Authors: Chang Liu, Siqi Tang, Kang An, Shengzhao Zhang, Yiling Zhou, Na Su, Rong Yang, Xiaoyang Liao, Zhenmei An, Sheyu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.634561/full
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author Chang Liu
Siqi Tang
Siqi Tang
Kang An
Shengzhao Zhang
Yiling Zhou
Na Su
Rong Yang
Xiaoyang Liao
Zhenmei An
Sheyu Li
Sheyu Li
Sheyu Li
author_facet Chang Liu
Siqi Tang
Siqi Tang
Kang An
Shengzhao Zhang
Yiling Zhou
Na Su
Rong Yang
Xiaoyang Liao
Zhenmei An
Sheyu Li
Sheyu Li
Sheyu Li
author_sort Chang Liu
collection DOAJ
description Background: Metformin extended-release (XR) is a once-daily alternative conventional immediate-release (IR) tablet for adults with type 2 diabetes.Aim: This study aimed to investigate the knowledge, attitude, and practice of the use of metformin XR tablets among clinicians.Methods: We conducted a cross-sectional online survey among endocrinologists, general practitioners, and internists, who are taking routine care of adults with type 2 diabetes in health institutes at all levels in Sichuan Province, China. We designed an online questionnaire including the demographic information, knowledge, attitude, and practice about metformin XR tablets.Results: We included 158 clinicians, 67.7% of whom were females and 63.9% were from tertiary hospitals. The median age was 39.6 years (ranging between 22 and 62 years). Only 8.2% of the clinicians correctly answered the knowledge questions, 82.3% and 62.0% of the responders assumed that metformin XR had superior efficacy and tolerability to the metformin IR, respectively. Only 46.8% of the clinicians prescribed the metformin XR based on the patient’s preference for once daily frequency.Conclusion: The knowledge, attitude, and practice of metformin XR among Chinese clinicians need improving. Clinicians need credible information to support their clinical decision-making regarding metformin XR.
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spelling doaj.art-2c1db18e89194143beb74809e00e50e32022-12-21T18:56:24ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122021-07-011210.3389/fphar.2021.634561634561Knowledge, Attitude, and Practice of Metformin Extended-Release Tablets Among Clinicians in China: A Cross-Sectional SurveyChang Liu0Siqi Tang1Siqi Tang2Kang An3Shengzhao Zhang4Yiling Zhou5Na Su6Rong Yang7Xiaoyang Liao8Zhenmei An9Sheyu Li10Sheyu Li11Sheyu Li12Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of General Medicine, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Pharmacy, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Pharmacy, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of General Medicine, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of General Medicine, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, ChinaDepartment of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, ChinaChinese Evidence-based Medicine Centre, Cochrane China Centre and MAGIC China Centre, West China Hospital, Sichuan University, Chengdu, ChinaEngineering Research Centre of Medical Information Technology, Ministry of Education, West China Hospital, Sichuan University, Chengdu, ChinaBackground: Metformin extended-release (XR) is a once-daily alternative conventional immediate-release (IR) tablet for adults with type 2 diabetes.Aim: This study aimed to investigate the knowledge, attitude, and practice of the use of metformin XR tablets among clinicians.Methods: We conducted a cross-sectional online survey among endocrinologists, general practitioners, and internists, who are taking routine care of adults with type 2 diabetes in health institutes at all levels in Sichuan Province, China. We designed an online questionnaire including the demographic information, knowledge, attitude, and practice about metformin XR tablets.Results: We included 158 clinicians, 67.7% of whom were females and 63.9% were from tertiary hospitals. The median age was 39.6 years (ranging between 22 and 62 years). Only 8.2% of the clinicians correctly answered the knowledge questions, 82.3% and 62.0% of the responders assumed that metformin XR had superior efficacy and tolerability to the metformin IR, respectively. Only 46.8% of the clinicians prescribed the metformin XR based on the patient’s preference for once daily frequency.Conclusion: The knowledge, attitude, and practice of metformin XR among Chinese clinicians need improving. Clinicians need credible information to support their clinical decision-making regarding metformin XR.https://www.frontiersin.org/articles/10.3389/fphar.2021.634561/fullmetformin XRknowledge—attitude—practiceclinicianmetformin immediate releaseadherence
spellingShingle Chang Liu
Siqi Tang
Siqi Tang
Kang An
Shengzhao Zhang
Yiling Zhou
Na Su
Rong Yang
Xiaoyang Liao
Zhenmei An
Sheyu Li
Sheyu Li
Sheyu Li
Knowledge, Attitude, and Practice of Metformin Extended-Release Tablets Among Clinicians in China: A Cross-Sectional Survey
Frontiers in Pharmacology
metformin XR
knowledge—attitude—practice
clinician
metformin immediate release
adherence
title Knowledge, Attitude, and Practice of Metformin Extended-Release Tablets Among Clinicians in China: A Cross-Sectional Survey
title_full Knowledge, Attitude, and Practice of Metformin Extended-Release Tablets Among Clinicians in China: A Cross-Sectional Survey
title_fullStr Knowledge, Attitude, and Practice of Metformin Extended-Release Tablets Among Clinicians in China: A Cross-Sectional Survey
title_full_unstemmed Knowledge, Attitude, and Practice of Metformin Extended-Release Tablets Among Clinicians in China: A Cross-Sectional Survey
title_short Knowledge, Attitude, and Practice of Metformin Extended-Release Tablets Among Clinicians in China: A Cross-Sectional Survey
title_sort knowledge attitude and practice of metformin extended release tablets among clinicians in china a cross sectional survey
topic metformin XR
knowledge—attitude—practice
clinician
metformin immediate release
adherence
url https://www.frontiersin.org/articles/10.3389/fphar.2021.634561/full
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