Genetic diversity and multiple introductions of porcine reproductive and respiratory syndrome viruses in Thailand
<p>Abstract</p> <p>Porcine reproductive and respiratory syndrome virus (PRRSV) is prevalent in Thailand, causing a huge impact on the country's swine industry. Yet the diversity and origin of these Thai PRRSVs remained vague. In this context, we collected all the Thai PRRSV se...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2011-04-01
|
| Series: | Virology Journal |
| Online Access: | http://www.virologyj.com/content/8/1/164 |
| _version_ | 1818484652211437568 |
|---|---|
| author | Thanawonguwech Roongroje Amonsin Alongkorn Ayudhya Suparlark NN Wong Charles LY Shi Mang Tun Hein M Leung Frederick CC |
| author_facet | Thanawonguwech Roongroje Amonsin Alongkorn Ayudhya Suparlark NN Wong Charles LY Shi Mang Tun Hein M Leung Frederick CC |
| author_sort | Thanawonguwech Roongroje |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Porcine reproductive and respiratory syndrome virus (PRRSV) is prevalent in Thailand, causing a huge impact on the country's swine industry. Yet the diversity and origin of these Thai PRRSVs remained vague. In this context, we collected all the Thai PRRSV sequences described earlier and incorporated them into the global diversity. The results indicated that PRRSVs in Thailand were originated from multiple introductions involving both Type 1 and Type 2 PRRSVs. Many of the introductions were followed by extensive geographic expansion, causing regional co-circulation of diverse PRRSV variants in three major pig-producing provinces. Based on these results, we suggest (1) to avoid blind vaccination and to apply vaccines tailor-made for target diversity, (2) to monitor pig importation and transportation, and (3) to implement a better biosecurity to reduce horizontal transmissions as three potentially effective strategies of controlling PRRS in Thailand.</p> |
| first_indexed | 2024-12-10T15:57:56Z |
| format | Article |
| id | doaj.art-2c1f9d676ce645c2a633397d063b3737 |
| institution | Directory Open Access Journal |
| issn | 1743-422X |
| language | English |
| last_indexed | 2024-12-10T15:57:56Z |
| publishDate | 2011-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Virology Journal |
| spelling | doaj.art-2c1f9d676ce645c2a633397d063b37372022-12-22T01:42:33ZengBMCVirology Journal1743-422X2011-04-018116410.1186/1743-422X-8-164Genetic diversity and multiple introductions of porcine reproductive and respiratory syndrome viruses in ThailandThanawonguwech RoongrojeAmonsin AlongkornAyudhya Suparlark NNWong Charles LYShi MangTun Hein MLeung Frederick CC<p>Abstract</p> <p>Porcine reproductive and respiratory syndrome virus (PRRSV) is prevalent in Thailand, causing a huge impact on the country's swine industry. Yet the diversity and origin of these Thai PRRSVs remained vague. In this context, we collected all the Thai PRRSV sequences described earlier and incorporated them into the global diversity. The results indicated that PRRSVs in Thailand were originated from multiple introductions involving both Type 1 and Type 2 PRRSVs. Many of the introductions were followed by extensive geographic expansion, causing regional co-circulation of diverse PRRSV variants in three major pig-producing provinces. Based on these results, we suggest (1) to avoid blind vaccination and to apply vaccines tailor-made for target diversity, (2) to monitor pig importation and transportation, and (3) to implement a better biosecurity to reduce horizontal transmissions as three potentially effective strategies of controlling PRRS in Thailand.</p>http://www.virologyj.com/content/8/1/164 |
| spellingShingle | Thanawonguwech Roongroje Amonsin Alongkorn Ayudhya Suparlark NN Wong Charles LY Shi Mang Tun Hein M Leung Frederick CC Genetic diversity and multiple introductions of porcine reproductive and respiratory syndrome viruses in Thailand Virology Journal |
| title | Genetic diversity and multiple introductions of porcine reproductive and respiratory syndrome viruses in Thailand |
| title_full | Genetic diversity and multiple introductions of porcine reproductive and respiratory syndrome viruses in Thailand |
| title_fullStr | Genetic diversity and multiple introductions of porcine reproductive and respiratory syndrome viruses in Thailand |
| title_full_unstemmed | Genetic diversity and multiple introductions of porcine reproductive and respiratory syndrome viruses in Thailand |
| title_short | Genetic diversity and multiple introductions of porcine reproductive and respiratory syndrome viruses in Thailand |
| title_sort | genetic diversity and multiple introductions of porcine reproductive and respiratory syndrome viruses in thailand |
| url | http://www.virologyj.com/content/8/1/164 |
| work_keys_str_mv | AT thanawonguwechroongroje geneticdiversityandmultipleintroductionsofporcinereproductiveandrespiratorysyndromevirusesinthailand AT amonsinalongkorn geneticdiversityandmultipleintroductionsofporcinereproductiveandrespiratorysyndromevirusesinthailand AT ayudhyasuparlarknn geneticdiversityandmultipleintroductionsofporcinereproductiveandrespiratorysyndromevirusesinthailand AT wongcharlesly geneticdiversityandmultipleintroductionsofporcinereproductiveandrespiratorysyndromevirusesinthailand AT shimang geneticdiversityandmultipleintroductionsofporcinereproductiveandrespiratorysyndromevirusesinthailand AT tunheinm geneticdiversityandmultipleintroductionsofporcinereproductiveandrespiratorysyndromevirusesinthailand AT leungfrederickcc geneticdiversityandmultipleintroductionsofporcinereproductiveandrespiratorysyndromevirusesinthailand |