Significance of C-Reactive Protein in Patients with ST-Elevation Myocardial Infarction Over Non-ST-Elevation Myocardial Infarction
Objective: To assess the use of C-reactive protein in patients with STEMI and NSTEMI to differentiate between the type of myocardial infarction at our hospital. Study Design: Comparative cross-sectional study. Place and Duration of Study: Department of Medicine, Pak Emirates Military Hospital...
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| Format: | Article |
| Language: | English |
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Army Medical College Rawalpindi
2023-01-01
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| Series: | Pakistan Armed Forces Medical Journal |
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| Online Access: | https://pafmj.org/index.php/PAFMJ/article/view/8873 |
| _version_ | 1828048777406054400 |
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| author | Shahzadi Anum Javed Ahmad Khan Fuad Ahmad Siddiqi Faryal Asmat |
| author_facet | Shahzadi Anum Javed Ahmad Khan Fuad Ahmad Siddiqi Faryal Asmat |
| author_sort | Shahzadi Anum |
| collection | DOAJ |
| description |
Objective: To assess the use of C-reactive protein in patients with STEMI and NSTEMI to differentiate between the type of myocardial infarction at our hospital.
Study Design: Comparative cross-sectional study.
Place and Duration of Study: Department of Medicine, Pak Emirates Military Hospital, Rawalpindi and Armed Force Institute of Cardiology & National Institute of Heart Disease, from Mar 2020 to Feb 2022.
Methodology: Patients diagnosed with MI by a consultant cardiologist were included in the study. They underwent all baseline investigations, including C reactive protein, at the time of presentation to a cardiac emergency. The treating consultant diagnosed MI (ST elevation or non-ST elevation) based on electrocardiogram findings. Values of C reactive protein and other socio-demographic variables were compared in both groups (patients with and without ST elevation MI).
Results: A total of 3500 patients with myocardial infarction were included in the final analysis. 2219(63.4%) had NSTEMI,while 1281(36.6%) had STEMI. Statistical analysis showed that C-reactive protein levels were not statistically different in both groups (p-value-0.375), but gender and Creatinine kinase myocardial bound levels were different in patients with non-ST elevation myocardial infarction and ST-elevation myocardial infarction (p-value<0.001).
Conclusion: Raised levels of C reactive protein were not statistically significantly different in ST-elevation myocardial infarction and non-ST elevation myocardial infarction patients. CKMB may give a better clue for differentiation between these two types of myocardial infarctions.
Keywords: Creactive protein, Non-ST-elevation myocardial infarction, ST-elevation myocardial infarction.
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| first_indexed | 2024-04-10T19:02:02Z |
| format | Article |
| id | doaj.art-2c1fd4b9500d4462a9f28e5c0bc44524 |
| institution | Directory Open Access Journal |
| issn | 0030-9648 2411-8842 |
| language | English |
| last_indexed | 2024-04-10T19:02:02Z |
| publishDate | 2023-01-01 |
| publisher | Army Medical College Rawalpindi |
| record_format | Article |
| series | Pakistan Armed Forces Medical Journal |
| spelling | doaj.art-2c1fd4b9500d4462a9f28e5c0bc445242023-01-31T08:19:33ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422023-01-0172610.51253/pafmj.v72i6.8873Significance of C-Reactive Protein in Patients with ST-Elevation Myocardial Infarction Over Non-ST-Elevation Myocardial InfarctionShahzadi Anum0Javed Ahmad Khan1Fuad Ahmad Siddiqi2Faryal Asmat3Combined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanCombined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanCombined Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanFauji Foundation Hospital, Rawalpindi Pakistan Objective: To assess the use of C-reactive protein in patients with STEMI and NSTEMI to differentiate between the type of myocardial infarction at our hospital. Study Design: Comparative cross-sectional study. Place and Duration of Study: Department of Medicine, Pak Emirates Military Hospital, Rawalpindi and Armed Force Institute of Cardiology & National Institute of Heart Disease, from Mar 2020 to Feb 2022. Methodology: Patients diagnosed with MI by a consultant cardiologist were included in the study. They underwent all baseline investigations, including C reactive protein, at the time of presentation to a cardiac emergency. The treating consultant diagnosed MI (ST elevation or non-ST elevation) based on electrocardiogram findings. Values of C reactive protein and other socio-demographic variables were compared in both groups (patients with and without ST elevation MI). Results: A total of 3500 patients with myocardial infarction were included in the final analysis. 2219(63.4%) had NSTEMI,while 1281(36.6%) had STEMI. Statistical analysis showed that C-reactive protein levels were not statistically different in both groups (p-value-0.375), but gender and Creatinine kinase myocardial bound levels were different in patients with non-ST elevation myocardial infarction and ST-elevation myocardial infarction (p-value<0.001). Conclusion: Raised levels of C reactive protein were not statistically significantly different in ST-elevation myocardial infarction and non-ST elevation myocardial infarction patients. CKMB may give a better clue for differentiation between these two types of myocardial infarctions. Keywords: Creactive protein, Non-ST-elevation myocardial infarction, ST-elevation myocardial infarction. https://pafmj.org/index.php/PAFMJ/article/view/8873Creactive proteinNon-ST-elevation myocardial infarctionST-elevation myocardial infarction |
| spellingShingle | Shahzadi Anum Javed Ahmad Khan Fuad Ahmad Siddiqi Faryal Asmat Significance of C-Reactive Protein in Patients with ST-Elevation Myocardial Infarction Over Non-ST-Elevation Myocardial Infarction Pakistan Armed Forces Medical Journal Creactive protein Non-ST-elevation myocardial infarction ST-elevation myocardial infarction |
| title | Significance of C-Reactive Protein in Patients with ST-Elevation Myocardial Infarction Over Non-ST-Elevation Myocardial Infarction |
| title_full | Significance of C-Reactive Protein in Patients with ST-Elevation Myocardial Infarction Over Non-ST-Elevation Myocardial Infarction |
| title_fullStr | Significance of C-Reactive Protein in Patients with ST-Elevation Myocardial Infarction Over Non-ST-Elevation Myocardial Infarction |
| title_full_unstemmed | Significance of C-Reactive Protein in Patients with ST-Elevation Myocardial Infarction Over Non-ST-Elevation Myocardial Infarction |
| title_short | Significance of C-Reactive Protein in Patients with ST-Elevation Myocardial Infarction Over Non-ST-Elevation Myocardial Infarction |
| title_sort | significance of c reactive protein in patients with st elevation myocardial infarction over non st elevation myocardial infarction |
| topic | Creactive protein Non-ST-elevation myocardial infarction ST-elevation myocardial infarction |
| url | https://pafmj.org/index.php/PAFMJ/article/view/8873 |
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