Changes in non-culprit lesion severity on follow-up coronary angiography after primary percutaneous coronary ıntervention
Aim: Non-culprit lesion severity has often been exaggerated at the time of acute ST segment elevation myocardial infarction (STEMI). We aimed to determine changes in non-culprit lesions severity on follow-up coronary angiography (CAG) and independent predictors of these changes. Material and Methods...
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| Format: | Article |
| Language: | English |
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Rabia Yılmaz
2021-07-01
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| Series: | Journal of Contemporary Medicine |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/download/article-file/1481104 |
| _version_ | 1797860604168372224 |
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| author | Aydın Yıldırım Selahattin Turen Fuat Caner |
| author_facet | Aydın Yıldırım Selahattin Turen Fuat Caner |
| author_sort | Aydın Yıldırım |
| collection | DOAJ |
| description | Aim: Non-culprit lesion severity has often been exaggerated at the time of acute ST segment elevation myocardial infarction (STEMI). We aimed to determine changes in non-culprit lesions severity on follow-up coronary angiography (CAG) and independent predictors of these changes.
Material and Methods: We retrospectively evaluated the changes in non-culprit lesion stenosis on follow-up CAG which was done within 2 months after primary percutaneous coronary intervention (P-PCI) in patients presenting with STEMI.
Results: 154 patients were included in this study and 207 non-culprit lesions (percentage diameter stenosis (PDS) ≥50%) were compared using quantitative coronary analyses (QCA). Minimal lumen diameter (1.30 ± 0.38 mm vs. 1.54 ± 0.46 mm, p lt;0.001) and reference vessel diameter (2.88 ± 0.66 mm vs. 2.92 ± 0.64 mm, p=0.001) were increased significantly and PDS (54.49 ± 9.38 vs. 47.5 ± 11.17, p lt;0.001) and percentage area stenosis (78.38 ± 8.65 vs. 71.29 ± 11.84, p= lt;0.001) were decreased significantly. There was no significant change in lesion length (13.52 ± 5.59 mm vs. 13.25 ± 5.31 mm, p= 0.078). 65 (31.4%) of these significant lesions (PDS ≥50% by QCA) were regressed (less than 50%) on follow-up CAG. In multivariable analyses; current smoking, clopidogrel use after the P-PCI and history of coronary artery disease were the independent predictors of decrease in PDS.
Conclusion: Significant exaggeration of non-culprit lesion stenosis severity occurs at the time of acute STEMI. |
| first_indexed | 2024-04-09T21:49:36Z |
| format | Article |
| id | doaj.art-2c20c57dfcbd45b9a91507bca0ab6dbd |
| institution | Directory Open Access Journal |
| issn | 2667-7180 |
| language | English |
| last_indexed | 2024-04-09T21:49:36Z |
| publishDate | 2021-07-01 |
| publisher | Rabia Yılmaz |
| record_format | Article |
| series | Journal of Contemporary Medicine |
| spelling | doaj.art-2c20c57dfcbd45b9a91507bca0ab6dbd2023-03-24T19:43:25ZengRabia YılmazJournal of Contemporary Medicine2667-71802021-07-0111453754210.16899/jcm.8512811809Changes in non-culprit lesion severity on follow-up coronary angiography after primary percutaneous coronary ınterventionAydın Yıldırım0Selahattin Turen1Fuat Caner2İstanbul Medipol ÜniversitesiSağlık Bilimleri Üniversitesi İstanbul Mehmet Akif Ersoy Göğüs Kalp ve Damar Cerrahisi Eğitim ve Araştırma HastanesiBatman Devlet HastanesiAim: Non-culprit lesion severity has often been exaggerated at the time of acute ST segment elevation myocardial infarction (STEMI). We aimed to determine changes in non-culprit lesions severity on follow-up coronary angiography (CAG) and independent predictors of these changes. Material and Methods: We retrospectively evaluated the changes in non-culprit lesion stenosis on follow-up CAG which was done within 2 months after primary percutaneous coronary intervention (P-PCI) in patients presenting with STEMI. Results: 154 patients were included in this study and 207 non-culprit lesions (percentage diameter stenosis (PDS) ≥50%) were compared using quantitative coronary analyses (QCA). Minimal lumen diameter (1.30 ± 0.38 mm vs. 1.54 ± 0.46 mm, p lt;0.001) and reference vessel diameter (2.88 ± 0.66 mm vs. 2.92 ± 0.64 mm, p=0.001) were increased significantly and PDS (54.49 ± 9.38 vs. 47.5 ± 11.17, p lt;0.001) and percentage area stenosis (78.38 ± 8.65 vs. 71.29 ± 11.84, p= lt;0.001) were decreased significantly. There was no significant change in lesion length (13.52 ± 5.59 mm vs. 13.25 ± 5.31 mm, p= 0.078). 65 (31.4%) of these significant lesions (PDS ≥50% by QCA) were regressed (less than 50%) on follow-up CAG. In multivariable analyses; current smoking, clopidogrel use after the P-PCI and history of coronary artery disease were the independent predictors of decrease in PDS. Conclusion: Significant exaggeration of non-culprit lesion stenosis severity occurs at the time of acute STEMI.https://dergipark.org.tr/tr/download/article-file/1481104primary percutaneous coronary interventionmulti-vessel diseasenon-culprit lesionquantitative coronary analysisprimer perkütan koroner girişimçoklu damar hastalığısorumlu olmayan lezyonkantitatif koroner analiz |
| spellingShingle | Aydın Yıldırım Selahattin Turen Fuat Caner Changes in non-culprit lesion severity on follow-up coronary angiography after primary percutaneous coronary ıntervention Journal of Contemporary Medicine primary percutaneous coronary intervention multi-vessel disease non-culprit lesion quantitative coronary analysis primer perkütan koroner girişim çoklu damar hastalığı sorumlu olmayan lezyon kantitatif koroner analiz |
| title | Changes in non-culprit lesion severity on follow-up coronary angiography after primary percutaneous coronary ıntervention |
| title_full | Changes in non-culprit lesion severity on follow-up coronary angiography after primary percutaneous coronary ıntervention |
| title_fullStr | Changes in non-culprit lesion severity on follow-up coronary angiography after primary percutaneous coronary ıntervention |
| title_full_unstemmed | Changes in non-culprit lesion severity on follow-up coronary angiography after primary percutaneous coronary ıntervention |
| title_short | Changes in non-culprit lesion severity on follow-up coronary angiography after primary percutaneous coronary ıntervention |
| title_sort | changes in non culprit lesion severity on follow up coronary angiography after primary percutaneous coronary intervention |
| topic | primary percutaneous coronary intervention multi-vessel disease non-culprit lesion quantitative coronary analysis primer perkütan koroner girişim çoklu damar hastalığı sorumlu olmayan lezyon kantitatif koroner analiz |
| url | https://dergipark.org.tr/tr/download/article-file/1481104 |
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