The Impact of COVID-19 on the Diagnosis and Treatment of Lung Cancer over a 2-Year Period at a Canadian Academic Center
Background: We have recently reported a 35% drop in new lung cancer diagnoses and a 64% drop in lung cancer surgeries during the first year of the pandemic. Methods: The target population was divided into three cohorts: pre-COVID-19 (2019), first year of COVID-19 (2020), and second year of COVID-19...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-11-01
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| Series: | Current Oncology |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1718-7729/29/11/684 |
| _version_ | 1797465561035177984 |
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| author | Goulnar Kasymjanova Angelo Rizzolo Carmela Pepe Jennifer E. Friedmann David Small Jonathan Spicer Magali Lecavalier-Barsoum Khalil Sultanem Hangjun Wang Alan Spatz Victor Cohen Jason S. Agulnik |
| author_facet | Goulnar Kasymjanova Angelo Rizzolo Carmela Pepe Jennifer E. Friedmann David Small Jonathan Spicer Magali Lecavalier-Barsoum Khalil Sultanem Hangjun Wang Alan Spatz Victor Cohen Jason S. Agulnik |
| author_sort | Goulnar Kasymjanova |
| collection | DOAJ |
| description | Background: We have recently reported a 35% drop in new lung cancer diagnoses and a 64% drop in lung cancer surgeries during the first year of the pandemic. Methods: The target population was divided into three cohorts: pre-COVID-19 (2019), first year of COVID-19 (2020), and second year of COVID-19 (2021). Results: The number of new lung cancer diagnoses during the second year of the pandemic increased by 75%, with more than 50% being in the advanced/metastatic stage. There was a significant increase in cases with multiple extrathoracic sites of metastases during the pandemic. During the first year of the pandemic, significantly more patients were treated with radiosurgery compared to the pre-COVID-19 year. During the second year, the number of radiosurgery and surgical cases returned to pre-COVID-19 levels. No significant changes were observed in systemic chemotherapy and targeted therapy. No statistical difference was identified in the mean wait time for diagnosis and treatment during the three years of observation. However, the wait time for surgery was prolonged compared to the pre-COVID-19 cohort. Conclusions: The significant drop in new diagnoses of lung cancer during the first year of the pandemic was followed by an almost two-fold increase in the second year, with the increased rate of metastatic disease with multiple extra-thoracic site metastases. Limited access to surgery resulted in the more frequent use of radiosurgery. |
| first_indexed | 2024-03-09T18:24:14Z |
| format | Article |
| id | doaj.art-2c226a78ae70407eb58bf1bc4be302a9 |
| institution | Directory Open Access Journal |
| issn | 1198-0052 1718-7729 |
| language | English |
| last_indexed | 2024-03-09T18:24:14Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj.art-2c226a78ae70407eb58bf1bc4be302a92023-11-24T08:03:11ZengMDPI AGCurrent Oncology1198-00521718-77292022-11-0129118677868510.3390/curroncol29110684The Impact of COVID-19 on the Diagnosis and Treatment of Lung Cancer over a 2-Year Period at a Canadian Academic CenterGoulnar Kasymjanova0Angelo Rizzolo1Carmela Pepe2Jennifer E. Friedmann3David Small4Jonathan Spicer5Magali Lecavalier-Barsoum6Khalil Sultanem7Hangjun Wang8Alan Spatz9Victor Cohen10Jason S. Agulnik11Peter Brojde Lung Cancer Centre, Jewish General Hospital, Montreal, QC H3T 1E2, CanadaPeter Brojde Lung Cancer Centre, Jewish General Hospital, Montreal, QC H3T 1E2, CanadaPeter Brojde Lung Cancer Centre, Jewish General Hospital, Montreal, QC H3T 1E2, CanadaPeter Brojde Lung Cancer Centre, Jewish General Hospital, Montreal, QC H3T 1E2, CanadaPeter Brojde Lung Cancer Centre, Jewish General Hospital, Montreal, QC H3T 1E2, CanadaDivision of Thoracic Thoracic Oncology, McGill University Health Centre, MUHC, Montreal, QC H4A 3S5, CanadaPeter Brojde Lung Cancer Centre, Jewish General Hospital, Montreal, QC H3T 1E2, CanadaPeter Brojde Lung Cancer Centre, Jewish General Hospital, Montreal, QC H3T 1E2, CanadaPeter Brojde Lung Cancer Centre, Jewish General Hospital, Montreal, QC H3T 1E2, CanadaPeter Brojde Lung Cancer Centre, Jewish General Hospital, Montreal, QC H3T 1E2, CanadaPeter Brojde Lung Cancer Centre, Jewish General Hospital, Montreal, QC H3T 1E2, CanadaPeter Brojde Lung Cancer Centre, Jewish General Hospital, Montreal, QC H3T 1E2, CanadaBackground: We have recently reported a 35% drop in new lung cancer diagnoses and a 64% drop in lung cancer surgeries during the first year of the pandemic. Methods: The target population was divided into three cohorts: pre-COVID-19 (2019), first year of COVID-19 (2020), and second year of COVID-19 (2021). Results: The number of new lung cancer diagnoses during the second year of the pandemic increased by 75%, with more than 50% being in the advanced/metastatic stage. There was a significant increase in cases with multiple extrathoracic sites of metastases during the pandemic. During the first year of the pandemic, significantly more patients were treated with radiosurgery compared to the pre-COVID-19 year. During the second year, the number of radiosurgery and surgical cases returned to pre-COVID-19 levels. No significant changes were observed in systemic chemotherapy and targeted therapy. No statistical difference was identified in the mean wait time for diagnosis and treatment during the three years of observation. However, the wait time for surgery was prolonged compared to the pre-COVID-19 cohort. Conclusions: The significant drop in new diagnoses of lung cancer during the first year of the pandemic was followed by an almost two-fold increase in the second year, with the increased rate of metastatic disease with multiple extra-thoracic site metastases. Limited access to surgery resulted in the more frequent use of radiosurgery.https://www.mdpi.com/1718-7729/29/11/684lung cancerCOVID-19wait timespattern of treatment |
| spellingShingle | Goulnar Kasymjanova Angelo Rizzolo Carmela Pepe Jennifer E. Friedmann David Small Jonathan Spicer Magali Lecavalier-Barsoum Khalil Sultanem Hangjun Wang Alan Spatz Victor Cohen Jason S. Agulnik The Impact of COVID-19 on the Diagnosis and Treatment of Lung Cancer over a 2-Year Period at a Canadian Academic Center Current Oncology lung cancer COVID-19 wait times pattern of treatment |
| title | The Impact of COVID-19 on the Diagnosis and Treatment of Lung Cancer over a 2-Year Period at a Canadian Academic Center |
| title_full | The Impact of COVID-19 on the Diagnosis and Treatment of Lung Cancer over a 2-Year Period at a Canadian Academic Center |
| title_fullStr | The Impact of COVID-19 on the Diagnosis and Treatment of Lung Cancer over a 2-Year Period at a Canadian Academic Center |
| title_full_unstemmed | The Impact of COVID-19 on the Diagnosis and Treatment of Lung Cancer over a 2-Year Period at a Canadian Academic Center |
| title_short | The Impact of COVID-19 on the Diagnosis and Treatment of Lung Cancer over a 2-Year Period at a Canadian Academic Center |
| title_sort | impact of covid 19 on the diagnosis and treatment of lung cancer over a 2 year period at a canadian academic center |
| topic | lung cancer COVID-19 wait times pattern of treatment |
| url | https://www.mdpi.com/1718-7729/29/11/684 |
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