Ternary WD40 repeat-containing protein complexes: evolution, composition and roles in plant immunity
Plants, like mammals, rely on their innate immune system to perceive and discriminate among the majority of their microbial pathogens. Unlike mammals, plants respond to this molecular dialogue by unleashing a complex chemical arsenal of defense metabolites to resist or evade pathogen infection. In b...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2016-01-01
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| Series: | Frontiers in Plant Science |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fpls.2015.01108/full |
| _version_ | 1818111349105885184 |
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| author | Jimi C. Miller William R. Chezem Nicole K. Clay |
| author_facet | Jimi C. Miller William R. Chezem Nicole K. Clay |
| author_sort | Jimi C. Miller |
| collection | DOAJ |
| description | Plants, like mammals, rely on their innate immune system to perceive and discriminate among the majority of their microbial pathogens. Unlike mammals, plants respond to this molecular dialogue by unleashing a complex chemical arsenal of defense metabolites to resist or evade pathogen infection. In basal or non-host resistance, plants utilize signal transduction pathways to detect non-self, damaged-self and altered-self-associated molecular patterns and translate these danger signals into largely inducible chemical defenses. The WD40 repeat (WDR)-containing proteins Gβ and TTG1 are constituents of two independent ternary protein complexes functioning at opposite ends of a plant immune signaling pathway. Gβ and TTG1 are also encoded by single-copy genes that are ubiquitous in higher plants, implying the limited diversity and functional conservation of their respective complexes. In this review, we summarize what is currently known about the evolutionary history of these WDR-containing ternary complexes, their repertoire and combinatorial interactions, and their downstream effectors and pathways in plant defense. |
| first_indexed | 2024-12-11T03:01:37Z |
| format | Article |
| id | doaj.art-2c23b02f374a45f9ba167a3e3e56f3e8 |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-12-11T03:01:37Z |
| publishDate | 2016-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-2c23b02f374a45f9ba167a3e3e56f3e82022-12-22T01:23:02ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2016-01-01610.3389/fpls.2015.01108168726Ternary WD40 repeat-containing protein complexes: evolution, composition and roles in plant immunityJimi C. Miller0William R. Chezem1Nicole K. Clay2YaleYaleYalePlants, like mammals, rely on their innate immune system to perceive and discriminate among the majority of their microbial pathogens. Unlike mammals, plants respond to this molecular dialogue by unleashing a complex chemical arsenal of defense metabolites to resist or evade pathogen infection. In basal or non-host resistance, plants utilize signal transduction pathways to detect non-self, damaged-self and altered-self-associated molecular patterns and translate these danger signals into largely inducible chemical defenses. The WD40 repeat (WDR)-containing proteins Gβ and TTG1 are constituents of two independent ternary protein complexes functioning at opposite ends of a plant immune signaling pathway. Gβ and TTG1 are also encoded by single-copy genes that are ubiquitous in higher plants, implying the limited diversity and functional conservation of their respective complexes. In this review, we summarize what is currently known about the evolutionary history of these WDR-containing ternary complexes, their repertoire and combinatorial interactions, and their downstream effectors and pathways in plant defense.http://journal.frontiersin.org/Journal/10.3389/fpls.2015.01108/fullDAMPsMAMPsplant innate immunityAnthocyaningbeta subunitProanthocyanidin |
| spellingShingle | Jimi C. Miller William R. Chezem Nicole K. Clay Ternary WD40 repeat-containing protein complexes: evolution, composition and roles in plant immunity Frontiers in Plant Science DAMPs MAMPs plant innate immunity Anthocyanin gbeta subunit Proanthocyanidin |
| title | Ternary WD40 repeat-containing protein complexes: evolution, composition and roles in plant immunity |
| title_full | Ternary WD40 repeat-containing protein complexes: evolution, composition and roles in plant immunity |
| title_fullStr | Ternary WD40 repeat-containing protein complexes: evolution, composition and roles in plant immunity |
| title_full_unstemmed | Ternary WD40 repeat-containing protein complexes: evolution, composition and roles in plant immunity |
| title_short | Ternary WD40 repeat-containing protein complexes: evolution, composition and roles in plant immunity |
| title_sort | ternary wd40 repeat containing protein complexes evolution composition and roles in plant immunity |
| topic | DAMPs MAMPs plant innate immunity Anthocyanin gbeta subunit Proanthocyanidin |
| url | http://journal.frontiersin.org/Journal/10.3389/fpls.2015.01108/full |
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