Observational studies: Ambient air pollution and hospitalization for RA-ILD in a heavily polluted city in China

Abstract. Little is known within the medical community about the impact of air pollution on hospital admissions due to rheumatoid arthritis associated with interstitial lung disease (RA-ILD). Our research aimed to explore whether there is a correlation and to estimate how the association was distrib...

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Main Authors: Baojin Liu, MS, Guangzhi Sun, MD, Ying Liu, MD, Yanfeng Hou, MD, Jianli Tao.
Format: Article
Language:English
Published: Wolters Kluwer 2022-05-01
Series:Medicine
Online Access:http://journals.lww.com/10.1097/MD.0000000000029309
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author Baojin Liu, MS
Guangzhi Sun, MD
Ying Liu, MD
Yanfeng Hou, MD
Jianli Tao.
author_facet Baojin Liu, MS
Guangzhi Sun, MD
Ying Liu, MD
Yanfeng Hou, MD
Jianli Tao.
author_sort Baojin Liu, MS
collection DOAJ
description Abstract. Little is known within the medical community about the impact of air pollution on hospital admissions due to rheumatoid arthritis associated with interstitial lung disease (RA-ILD). Our research aimed to explore whether there is a correlation and to estimate how the association was distributed across various lags in Jinan, China. The relationships between ambient air pollutant concentrations, including PM2.5, PM10, sulfur dioxide (SO2), ozone (O3), and nitrogen dioxide (NO2), and monthly hospitalizations for RA-ILD were studied by employing a general linear model with a Poisson distribution. This time-series study was performed from January 1st, 2015 to December 31st, 2019. In the 5-year study, there were 221 hospitalizations for RA-ILD in Jinan city. The levels of PM2.5, PM10, SO2, and NO2 were significantly related to the number of admissions for RA-ILD. PM2.5, PM10, and SO2 showed the most significant effect on the month (lag 0), and NO2 was most related to RA-ILD at a lag of two months (lag 2). The monthly admissions of RA-ILD increased by 0.875% (95% CI: 0.375–1.377%), 0.548% (95% CI: 0.148–0.949%), 1.968% (95% CI: 0.869–3.080%), and 1.534% (95% CI: 0.305–2.778%) for each 10 μg/m3 increase in PM2.5, PM10, SO2 and NO2, respectively. This study might add more detailed evidence that higher levels of PM2.5, PM10, SO2 and NO2 increase the risk of hospitalizations for RA-ILD. Further study of the role of air pollution in the pathogenesis of RA-ILD is warranted.
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spelling doaj.art-2c2a87ae049145dc9e230bf8836456282022-12-22T00:29:03ZengWolters KluwerMedicine0025-79741536-59642022-05-0110119e2930910.1097/MD.0000000000029309202205130-00012Observational studies: Ambient air pollution and hospitalization for RA-ILD in a heavily polluted city in ChinaBaojin Liu, MSGuangzhi Sun, MDYing Liu, MDYanfeng Hou, MDJianli Tao.Abstract. Little is known within the medical community about the impact of air pollution on hospital admissions due to rheumatoid arthritis associated with interstitial lung disease (RA-ILD). Our research aimed to explore whether there is a correlation and to estimate how the association was distributed across various lags in Jinan, China. The relationships between ambient air pollutant concentrations, including PM2.5, PM10, sulfur dioxide (SO2), ozone (O3), and nitrogen dioxide (NO2), and monthly hospitalizations for RA-ILD were studied by employing a general linear model with a Poisson distribution. This time-series study was performed from January 1st, 2015 to December 31st, 2019. In the 5-year study, there were 221 hospitalizations for RA-ILD in Jinan city. The levels of PM2.5, PM10, SO2, and NO2 were significantly related to the number of admissions for RA-ILD. PM2.5, PM10, and SO2 showed the most significant effect on the month (lag 0), and NO2 was most related to RA-ILD at a lag of two months (lag 2). The monthly admissions of RA-ILD increased by 0.875% (95% CI: 0.375–1.377%), 0.548% (95% CI: 0.148–0.949%), 1.968% (95% CI: 0.869–3.080%), and 1.534% (95% CI: 0.305–2.778%) for each 10 μg/m3 increase in PM2.5, PM10, SO2 and NO2, respectively. This study might add more detailed evidence that higher levels of PM2.5, PM10, SO2 and NO2 increase the risk of hospitalizations for RA-ILD. Further study of the role of air pollution in the pathogenesis of RA-ILD is warranted.http://journals.lww.com/10.1097/MD.0000000000029309
spellingShingle Baojin Liu, MS
Guangzhi Sun, MD
Ying Liu, MD
Yanfeng Hou, MD
Jianli Tao.
Observational studies: Ambient air pollution and hospitalization for RA-ILD in a heavily polluted city in China
Medicine
title Observational studies: Ambient air pollution and hospitalization for RA-ILD in a heavily polluted city in China
title_full Observational studies: Ambient air pollution and hospitalization for RA-ILD in a heavily polluted city in China
title_fullStr Observational studies: Ambient air pollution and hospitalization for RA-ILD in a heavily polluted city in China
title_full_unstemmed Observational studies: Ambient air pollution and hospitalization for RA-ILD in a heavily polluted city in China
title_short Observational studies: Ambient air pollution and hospitalization for RA-ILD in a heavily polluted city in China
title_sort observational studies ambient air pollution and hospitalization for ra ild in a heavily polluted city in china
url http://journals.lww.com/10.1097/MD.0000000000029309
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