Targeting the mRNA endonuclease CPSF73 inhibits breast cancer cell migration, invasion, and self-renewal
Summary: Cleavage by the endonuclease CPSF73 and polyadenylation of nascent RNA is an essential step in co-transcriptional mRNA maturation. Recent work has surprisingly identified CPSF73 as a promising drug target for inhibiting the growth of specific cancers, triggering further studies on understan...
| Príomhchruthaitheoirí: | , , |
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| Formáid: | Alt |
| Teanga: | English |
| Foilsithe / Cruthaithe: |
Elsevier
2022-08-01
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| Sraith: | iScience |
| Ábhair: | |
| Rochtain ar líne: | http://www.sciencedirect.com/science/article/pii/S2589004222010768 |