RDC complex executes a dynamic piRNA program during Drosophila spermatogenesis to safeguard male fertility.

piRNAs are small non-coding RNAs that guide the silencing of transposons and other targets in animal gonads. In Drosophila female germline, many piRNA source loci dubbed "piRNA clusters" lack hallmarks of active genes and exploit an alternative path for transcription, which relies on the R...

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Bibliographic Details
Main Authors: Peiwei Chen, Yicheng Luo, Alexei A Aravin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-09-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009591