Aceclofenac in the treatment of diseases of the locomotor apparatus
The paper highlights data on the mechanisms of action and efficacy of aceclofenac in chronic inflammatory diseases of the joint and spine (rheumatoid arthritis, spondyloarthritis) and osteoarthritis (OA). It shows the comparable efficacy of aceclofenac and nonselective nonsteroidal anti-inflammatory...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
IMA-PRESS LLC
2017-09-01
|
| Series: | Современная ревматология |
| Subjects: | |
| Online Access: | https://mrj.ima-press.net/mrj/article/view/782 |
| _version_ | 1797876732450045952 |
|---|---|
| author | E. V. Igolkina N. V. Chichasova G. R. Imametdinova |
| author_facet | E. V. Igolkina N. V. Chichasova G. R. Imametdinova |
| author_sort | E. V. Igolkina |
| collection | DOAJ |
| description | The paper highlights data on the mechanisms of action and efficacy of aceclofenac in chronic inflammatory diseases of the joint and spine (rheumatoid arthritis, spondyloarthritis) and osteoarthritis (OA). It shows the comparable efficacy of aceclofenac and nonselective nonsteroidal anti-inflammatory drugs in different rheumatic diseases. Randomized controlled trials and meta-analyses have revealed the high gastrointestinal safety of aceclofenac, which is comparable with that of celecoxib, including the low risk of gastrointestinal bleeding. Since aceclofenac has no negative effect on the articular cartilage and has a good tolerability, it may be given to persons of any age, including long-term use, which does not affect the safety of treatment. |
| first_indexed | 2024-04-10T02:07:13Z |
| format | Article |
| id | doaj.art-2c30c5df70ee4c699441bddff6cc19e2 |
| institution | Directory Open Access Journal |
| issn | 1996-7012 2310-158X |
| language | Russian |
| last_indexed | 2024-04-10T02:07:13Z |
| publishDate | 2017-09-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Современная ревматология |
| spelling | doaj.art-2c30c5df70ee4c699441bddff6cc19e22023-03-13T08:39:25ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2017-09-011139910510.14412/1996-7012-2017-3-99-1052055Aceclofenac in the treatment of diseases of the locomotor apparatusE. V. Igolkina0N. V. Chichasova1G. R. Imametdinova2ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава РоссииФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава РоссииФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава РоссииThe paper highlights data on the mechanisms of action and efficacy of aceclofenac in chronic inflammatory diseases of the joint and spine (rheumatoid arthritis, spondyloarthritis) and osteoarthritis (OA). It shows the comparable efficacy of aceclofenac and nonselective nonsteroidal anti-inflammatory drugs in different rheumatic diseases. Randomized controlled trials and meta-analyses have revealed the high gastrointestinal safety of aceclofenac, which is comparable with that of celecoxib, including the low risk of gastrointestinal bleeding. Since aceclofenac has no negative effect on the articular cartilage and has a good tolerability, it may be given to persons of any age, including long-term use, which does not affect the safety of treatment.https://mrj.ima-press.net/mrj/article/view/782нестероидные противовоспалительные препаратыацеклофенакэффективностьпереносимостьхроническая и острая боль |
| spellingShingle | E. V. Igolkina N. V. Chichasova G. R. Imametdinova Aceclofenac in the treatment of diseases of the locomotor apparatus Современная ревматология нестероидные противовоспалительные препараты ацеклофенак эффективность переносимость хроническая и острая боль |
| title | Aceclofenac in the treatment of diseases of the locomotor apparatus |
| title_full | Aceclofenac in the treatment of diseases of the locomotor apparatus |
| title_fullStr | Aceclofenac in the treatment of diseases of the locomotor apparatus |
| title_full_unstemmed | Aceclofenac in the treatment of diseases of the locomotor apparatus |
| title_short | Aceclofenac in the treatment of diseases of the locomotor apparatus |
| title_sort | aceclofenac in the treatment of diseases of the locomotor apparatus |
| topic | нестероидные противовоспалительные препараты ацеклофенак эффективность переносимость хроническая и острая боль |
| url | https://mrj.ima-press.net/mrj/article/view/782 |
| work_keys_str_mv | AT evigolkina aceclofenacinthetreatmentofdiseasesofthelocomotorapparatus AT nvchichasova aceclofenacinthetreatmentofdiseasesofthelocomotorapparatus AT grimametdinova aceclofenacinthetreatmentofdiseasesofthelocomotorapparatus |