Formulation of Transliposomal Nanocarrier Gel Containing Strychnine for the Effective Management of Skin Cancer
Strychnine (STCN) has demonstrated an exceptional anticancer effect against various cancers. However, the STCN clinical utility has been hampered by its low water solubility, restricted therapeutic window, short half-life, and significant toxicity. The objective of this investigation was to design a...
Main Authors: | Perwez Alam, Mohd Imran, Dipak Kumar Gupta, Ali Akhtar |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-10-01
|
Series: | Gels |
Subjects: | |
Online Access: | https://www.mdpi.com/2310-2861/9/10/831 |
Similar Items
-
Design, statistical optimization, and characterization of Esculin-loaded transliposome nanogel for topical delivery: In-vitro, ex vivo study and dermatokinetic evaluation
by: Abdullah S. Alshetaili
Published: (2024-05-01) -
Bitter nemesis : the intimate history of strychnine /
by: 344578 Buckingham, John
Published: (2008) -
The Production and Evaluation of an Electrochemical Sensors for Strychnine and Its Main Metabolite Strychnine N-Oxide for Their Use in Biological Samples
by: Bakhtiyar Qader, et al.
Published: (2022-03-01) -
Ion-Pair Compounds of Strychnine for Enhancing Skin Permeability: Influencing the Transdermal Processes In Vitro Based on Molecular Simulation
by: Lili He, et al.
Published: (2021-12-01) -
Effect of Hydroalcoholic Extract of Cinnamomum on Strychnine-Induced Seizure in Mice
by: Saba Ghaderkhani, et al.
Published: (2014-10-01)