Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes
<p>Abstract</p> <p>Background</p> <p>The human cell cycle transcription factor FOXM1 is known to play a key role in regulating timely mitotic progression and accurate chromosomal segregation during cell division. Deregulation of FOXM1 has been linked to a majority of hu...
Main Authors: | Philpott Michael P, Young Bryan D, Chaplin Tracy, Gemenetzidis Emilios, Teh Muy-Teck |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2010-02-01
|
Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/9/1/45 |
Similar Items
-
FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation.
by: Emilios Gemenetzidis, et al.
Published: (2009-01-01) -
FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma.
by: Muy-Teck Teh, et al.
Published: (2012-01-01) -
FOXM1 coming of age: Time for translation into clinical benefits?
by: Muy-Teck eTeh
Published: (2012-10-01) -
Two mechanisms regulate keratin K15 expression in keratinocytes: role of PKC/AP-1 and FOXM1 mediated signalling.
by: Amrita Bose, et al.
Published: (2012-01-01) -
Replication stress and FOXM1 drive radiation induced genomic instability and cell transformation.
by: Zhentian Li, et al.
Published: (2020-01-01)