Multi-State Models for Panel Data: The msm Package for R

Panel data are observations of a continuous-time process at arbitrary times, for example, visits to a hospital to diagnose disease status. Multi-state models for such data are generally based on the Markov assumption. This article reviews the range of Markov models and their extensions which can be...

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Main Author: Christopher H. Jackson
Format: Article
Language:English
Published: Foundation for Open Access Statistics 2011-01-01
Series:Journal of Statistical Software
Subjects:
Online Access:http://www.jstatsoft.org/v38/i08/paper
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author Christopher H. Jackson
author_facet Christopher H. Jackson
author_sort Christopher H. Jackson
collection DOAJ
description Panel data are observations of a continuous-time process at arbitrary times, for example, visits to a hospital to diagnose disease status. Multi-state models for such data are generally based on the Markov assumption. This article reviews the range of Markov models and their extensions which can be fitted to panel-observed data, and their implementation in the msm package for R. Transition intensities may vary between individuals, or with piecewise-constant time-dependent covariates, giving an inhomogeneous Markov model. Hidden Markov models can be used for multi-state processes which are misclassified or observed only through a noisy marker. The package is intended to be straightforward to use, flexible and comprehensively documented. Worked examples are given of the use of msm to model chronic disease progression and screening. Assessment of model fit, and potential future developments of the software, are also discussed.
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spelling doaj.art-2c3888d9832d4508bc97963fd31cedcd2022-12-22T02:04:29ZengFoundation for Open Access StatisticsJournal of Statistical Software1548-76602011-01-013808Multi-State Models for Panel Data: The msm Package for RChristopher H. JacksonPanel data are observations of a continuous-time process at arbitrary times, for example, visits to a hospital to diagnose disease status. Multi-state models for such data are generally based on the Markov assumption. This article reviews the range of Markov models and their extensions which can be fitted to panel-observed data, and their implementation in the msm package for R. Transition intensities may vary between individuals, or with piecewise-constant time-dependent covariates, giving an inhomogeneous Markov model. Hidden Markov models can be used for multi-state processes which are misclassified or observed only through a noisy marker. The package is intended to be straightforward to use, flexible and comprehensively documented. Worked examples are given of the use of msm to model chronic disease progression and screening. Assessment of model fit, and potential future developments of the software, are also discussed.http://www.jstatsoft.org/v38/i08/papermulti-state modelsMarkov modelspanel dataRmsm
spellingShingle Christopher H. Jackson
Multi-State Models for Panel Data: The msm Package for R
Journal of Statistical Software
multi-state models
Markov models
panel data
R
msm
title Multi-State Models for Panel Data: The msm Package for R
title_full Multi-State Models for Panel Data: The msm Package for R
title_fullStr Multi-State Models for Panel Data: The msm Package for R
title_full_unstemmed Multi-State Models for Panel Data: The msm Package for R
title_short Multi-State Models for Panel Data: The msm Package for R
title_sort multi state models for panel data the msm package for r
topic multi-state models
Markov models
panel data
R
msm
url http://www.jstatsoft.org/v38/i08/paper
work_keys_str_mv AT christopherhjackson multistatemodelsforpaneldatathemsmpackageforr