A descriptive study of hyponatremia in a tertiary care hospital of Eastern India
Background: Hyponatremia is one of the commonest electrolyte disturbances encountered in medical wards and contributes to substantial morbidity and mortality. However, early recognition and management drastically alters prognosis. Therefore, this observational study was taken up to explore the clini...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2012-01-01
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| Series: | Indian Journal of Endocrinology and Metabolism |
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| Online Access: | http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=2;spage=288;epage=291;aulast=Chatterjee |
| _version_ | 1818134883293200384 |
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| author | Nandini Chatterjee Nilanjan Sengupta Chanchal Das Atanu Roy Chowdhuri Ashis Kumar Basu Salil Kumar Pal |
| author_facet | Nandini Chatterjee Nilanjan Sengupta Chanchal Das Atanu Roy Chowdhuri Ashis Kumar Basu Salil Kumar Pal |
| author_sort | Nandini Chatterjee |
| collection | DOAJ |
| description | Background: Hyponatremia is one of the commonest electrolyte disturbances encountered in medical wards and contributes to substantial morbidity and mortality. However, early recognition and management drastically alters prognosis. Therefore, this observational study was taken up to explore the clinical profile of hyponatremia. Aim: To assess the incidence and clinical profile of hyponatremia in medically ill patients. Materials and Methods: This observational study was conducted in the medical ward of a tertiary care hospital from March 2010 to April 2011. All patients underwent routine hemogram, blood biochemistry, serum electrolytes, thyroid function tests, and morning serum cortisol estimation. This was followed by a plasma and urinary osmolality determination (osmometer 800 CL) as well as urinary sodium estimation. Patients were diagnosed to have syndrome of inappropriate antidiuretic hormone secretion (SIADH) if they satisfied the Bartter and Schwartz criteria. Results: 201 patients (16.4%) had a serum Na < 135 meq/l. There were 126 (62.69%) male patients and 75 (37.31%) female patients. Severe hyponatremia (Na < 120 meq/l) was detected in 30 patients (2.4%). The largest group of hyponatremic patients were euvolemic [102 (50.74%)], followed by hypervolemic [54 (26.86%)] and hypovolemic [45 (22.4%)]. Sixty-six patients fulfilled the criteria for SIADH. The most common underlying predisposing factor for hyponatremia in our case series was fluid loss by vomiting/diarrhea. During the hospital stay, 13.5% (15/201) hyponatremic patients died, while the corresponding figure in normonatremic patients was 8.5% (87/1020). Conclusion: The incidence of hyponatremia in our series was higher than values mostly reported in western literature. Euvolemic hyponatremia was the most common type, a significant fraction of which is SIADH. |
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| format | Article |
| id | doaj.art-2c3894a01e104ee2945f4d4a675afe2d |
| institution | Directory Open Access Journal |
| issn | 2230-8210 2230-9500 |
| language | English |
| last_indexed | 2024-12-11T09:15:41Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
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| series | Indian Journal of Endocrinology and Metabolism |
| spelling | doaj.art-2c3894a01e104ee2945f4d4a675afe2d2022-12-22T01:13:22ZengWolters Kluwer Medknow PublicationsIndian Journal of Endocrinology and Metabolism2230-82102230-95002012-01-0116228829110.4103/2230-8210.93757A descriptive study of hyponatremia in a tertiary care hospital of Eastern IndiaNandini ChatterjeeNilanjan SenguptaChanchal DasAtanu Roy ChowdhuriAshis Kumar BasuSalil Kumar PalBackground: Hyponatremia is one of the commonest electrolyte disturbances encountered in medical wards and contributes to substantial morbidity and mortality. However, early recognition and management drastically alters prognosis. Therefore, this observational study was taken up to explore the clinical profile of hyponatremia. Aim: To assess the incidence and clinical profile of hyponatremia in medically ill patients. Materials and Methods: This observational study was conducted in the medical ward of a tertiary care hospital from March 2010 to April 2011. All patients underwent routine hemogram, blood biochemistry, serum electrolytes, thyroid function tests, and morning serum cortisol estimation. This was followed by a plasma and urinary osmolality determination (osmometer 800 CL) as well as urinary sodium estimation. Patients were diagnosed to have syndrome of inappropriate antidiuretic hormone secretion (SIADH) if they satisfied the Bartter and Schwartz criteria. Results: 201 patients (16.4%) had a serum Na < 135 meq/l. There were 126 (62.69%) male patients and 75 (37.31%) female patients. Severe hyponatremia (Na < 120 meq/l) was detected in 30 patients (2.4%). The largest group of hyponatremic patients were euvolemic [102 (50.74%)], followed by hypervolemic [54 (26.86%)] and hypovolemic [45 (22.4%)]. Sixty-six patients fulfilled the criteria for SIADH. The most common underlying predisposing factor for hyponatremia in our case series was fluid loss by vomiting/diarrhea. During the hospital stay, 13.5% (15/201) hyponatremic patients died, while the corresponding figure in normonatremic patients was 8.5% (87/1020). Conclusion: The incidence of hyponatremia in our series was higher than values mostly reported in western literature. Euvolemic hyponatremia was the most common type, a significant fraction of which is SIADH.http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=2;spage=288;epage=291;aulast=ChatterjeeEuvolemichyponatremiasyndrome of inappropriate antidiuretic hormone secretion |
| spellingShingle | Nandini Chatterjee Nilanjan Sengupta Chanchal Das Atanu Roy Chowdhuri Ashis Kumar Basu Salil Kumar Pal A descriptive study of hyponatremia in a tertiary care hospital of Eastern India Indian Journal of Endocrinology and Metabolism Euvolemic hyponatremia syndrome of inappropriate antidiuretic hormone secretion |
| title | A descriptive study of hyponatremia in a tertiary care hospital of Eastern India |
| title_full | A descriptive study of hyponatremia in a tertiary care hospital of Eastern India |
| title_fullStr | A descriptive study of hyponatremia in a tertiary care hospital of Eastern India |
| title_full_unstemmed | A descriptive study of hyponatremia in a tertiary care hospital of Eastern India |
| title_short | A descriptive study of hyponatremia in a tertiary care hospital of Eastern India |
| title_sort | descriptive study of hyponatremia in a tertiary care hospital of eastern india |
| topic | Euvolemic hyponatremia syndrome of inappropriate antidiuretic hormone secretion |
| url | http://www.ijem.in/article.asp?issn=2230-8210;year=2012;volume=16;issue=2;spage=288;epage=291;aulast=Chatterjee |
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