Investigation of Predictive Value of Complete Blood Count in the Diagnosis of Acute Complicated Appendicitis
Aim:Whether it is possible to differentiate complicated from uncomplicated acute appendicitis (AA) by using complete blood count (CBC) is controversial. In this study, we analysed the predictive value of CBC in differentiating complicated from uncomplicated AA.Methods:In this retrospective study, we...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2019-03-01
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| Series: | Haseki Tıp Bülteni |
| Subjects: | |
| Online Access: |
http://www.hasekidergisi.com/archives/archive-detail/article-preview/nvestigation-of-predictive-value-of-complete-blood/25861
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| Summary: | Aim:Whether it is possible to differentiate complicated from uncomplicated acute appendicitis (AA) by using complete blood count (CBC) is controversial. In this study, we analysed the predictive value of CBC in differentiating complicated from uncomplicated AA.Methods:In this retrospective study, we analyzed records of patients who underwent appendectomy in our clinic between January 1, 2015 and January 1, 2018. The demographic data and CBC reports were collected.Results:Two hundred thirty-five patients underwent appendectomy due to AA. Of the 235 patients, 164 (69.8%) had non-complicated and 71 (30.2%) had complicated AA. The mean white blood count (WBC), red cell distribution width (RDW), platelet and plateletcrit count were significantly higher in patients with complicated AA than in those with uncomplicated AA (p=0.001; p<0.01, p=0.049, and p=0.006, respectively). Both the mean neutrophil count and percentage were statistically higher in complicated AA patients (p=0.001 and p<0.01, respectively). The basophil-to-lymphocyte ratio (BLR) and neutrophilto- lymphocyte ratio (NLR) were significantly higher in patients with complicated AA (p=0.001 and p<0.01, respectively). Logistic regression analysis showed that WBC and RDW were independent diagnostic factors for complicated AA [odss ratio (OR) 5.079 (95% confidence interval (CI): 2.29-11.24 and OR 1.412 (95% CI: 1.1-1.98), respectively] (p<0.001 and p=0.046, respectively). The sensitivity, specificity, positive and negative predictive values in complicated AA for BLR were 67.35%, 64.04%, 44.6% and 82%, and for NLR were 73.47%, 66.67%, 48.6% and 85.4%, respectively.Conclusion:Elevated NLR, BLR and RDW, WBC and neutrophil count may help differentiate complicated from non-complicated AA. |
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| ISSN: | 1302-0072 2147-2688 |