D-dimer measurements in acute aortic dissection
Acute aortic dissection (AAD) is a medical emergency with significant morbidity and mortality. The diagnosis can be challenging due to the wide array of presenting symptoms and a broad differential diagnosis. Computed tomographic angiography is currently the gold standard for diagnosis of AAD. Howev...
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| Format: | Article |
| Language: | English |
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Southwest Respiratory and Critical Care Chronicles
2016-07-01
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| Series: | Southwest Respiratory and Critical Care Chronicles |
| Subjects: | |
| Online Access: | http://pulmonarychronicles.com/index.php/pulmonarychronicles/article/view/282 |
| _version_ | 1818987669702574080 |
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| author | Vladyslava Bazylevska Alvaro Rosales Scott Shurmur |
| author_facet | Vladyslava Bazylevska Alvaro Rosales Scott Shurmur |
| author_sort | Vladyslava Bazylevska |
| collection | DOAJ |
| description | Acute aortic dissection (AAD) is a medical emergency with significant morbidity and mortality. The diagnosis can be challenging due to the wide array of presenting symptoms and a broad differential diagnosis. Computed tomographic angiography is currently the gold standard for diagnosis of AAD. However, it carries the risk of contrast and radiation exposure and has a financial burden for patients. Multiple biomarkers have been evaluated as a screening tool for AAD. D-dimer has previously been suggested as a sole rule-out test for AAD. It is rapid and inexpensive, is widely available in the emergency rooms, and is highly sensitive for any thrombotic event. This review article evaluates the evidence for the use of D-dimer assays in the diagnosis of AAD, in differentiation of AAD from acute coronary syndromes, and in risk stratification of AAD patients. |
| first_indexed | 2024-12-20T19:10:22Z |
| format | Article |
| id | doaj.art-2c3a66e5b2da4d74bf01482ba0b89c2c |
| institution | Directory Open Access Journal |
| issn | 2325-9205 |
| language | English |
| last_indexed | 2024-12-20T19:10:22Z |
| publishDate | 2016-07-01 |
| publisher | Southwest Respiratory and Critical Care Chronicles |
| record_format | Article |
| series | Southwest Respiratory and Critical Care Chronicles |
| spelling | doaj.art-2c3a66e5b2da4d74bf01482ba0b89c2c2022-12-21T19:29:13ZengSouthwest Respiratory and Critical Care ChroniclesSouthwest Respiratory and Critical Care Chronicles2325-92052016-07-014153846264D-dimer measurements in acute aortic dissectionVladyslava Bazylevska0Alvaro RosalesScott ShurmurDepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock TXAcute aortic dissection (AAD) is a medical emergency with significant morbidity and mortality. The diagnosis can be challenging due to the wide array of presenting symptoms and a broad differential diagnosis. Computed tomographic angiography is currently the gold standard for diagnosis of AAD. However, it carries the risk of contrast and radiation exposure and has a financial burden for patients. Multiple biomarkers have been evaluated as a screening tool for AAD. D-dimer has previously been suggested as a sole rule-out test for AAD. It is rapid and inexpensive, is widely available in the emergency rooms, and is highly sensitive for any thrombotic event. This review article evaluates the evidence for the use of D-dimer assays in the diagnosis of AAD, in differentiation of AAD from acute coronary syndromes, and in risk stratification of AAD patients.http://pulmonarychronicles.com/index.php/pulmonarychronicles/article/view/282aortic dissectionD-dimerdiagnosis |
| spellingShingle | Vladyslava Bazylevska Alvaro Rosales Scott Shurmur D-dimer measurements in acute aortic dissection Southwest Respiratory and Critical Care Chronicles aortic dissection D-dimer diagnosis |
| title | D-dimer measurements in acute aortic dissection |
| title_full | D-dimer measurements in acute aortic dissection |
| title_fullStr | D-dimer measurements in acute aortic dissection |
| title_full_unstemmed | D-dimer measurements in acute aortic dissection |
| title_short | D-dimer measurements in acute aortic dissection |
| title_sort | d dimer measurements in acute aortic dissection |
| topic | aortic dissection D-dimer diagnosis |
| url | http://pulmonarychronicles.com/index.php/pulmonarychronicles/article/view/282 |
| work_keys_str_mv | AT vladyslavabazylevska ddimermeasurementsinacuteaorticdissection AT alvarorosales ddimermeasurementsinacuteaorticdissection AT scottshurmur ddimermeasurementsinacuteaorticdissection |