Gene network downstream plant stress response modulated by peroxisomal H2O2
Reactive oxygen species (ROS) act as secondary messengers that can be sensed by specific redox-sensitive proteins responsible for the activation of signal transduction culminating in altered gene expression. The subcellular site, in which modifications in the ROS/oxidation state occur, can also act...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Plant Science |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpls.2022.930721/full |
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| author | Laura C. Terrón-Camero M. Ángeles Peláez-Vico A. Rodríguez-González Coral del Val Coral del Val Luisa M. Sandalio María C. Romero-Puertas |
| author_facet | Laura C. Terrón-Camero M. Ángeles Peláez-Vico A. Rodríguez-González Coral del Val Coral del Val Luisa M. Sandalio María C. Romero-Puertas |
| author_sort | Laura C. Terrón-Camero |
| collection | DOAJ |
| description | Reactive oxygen species (ROS) act as secondary messengers that can be sensed by specific redox-sensitive proteins responsible for the activation of signal transduction culminating in altered gene expression. The subcellular site, in which modifications in the ROS/oxidation state occur, can also act as a specific cellular redox network signal. The chemical identity of ROS and their subcellular origin is actually a specific imprint on the transcriptome response. In recent years, a number of transcriptomic studies related to altered ROS metabolism in plant peroxisomes have been carried out. In this study, we conducted a meta-analysis of these transcriptomic findings to identify common transcriptional footprints for plant peroxisomal-dependent signaling at early and later time points. These footprints highlight the regulation of various metabolic pathways and gene families, which are also found in plant responses to several abiotic stresses. Major peroxisomal-dependent genes are associated with protein and endoplasmic reticulum (ER) protection at later stages of stress while, at earlier stages, these genes are related to hormone biosynthesis and signaling regulation. Furthermore, in silico analyses allowed us to assign human orthologs to some of the peroxisomal-dependent proteins, which are mainly associated with different cancer pathologies. Peroxisomal footprints provide a valuable resource for assessing and supporting key peroxisomal functions in cellular metabolism under control and stress conditions across species. |
| first_indexed | 2024-04-13T18:25:25Z |
| format | Article |
| id | doaj.art-2c3b7859c39c4b158fa3932cfbfe1e98 |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-04-13T18:25:25Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-2c3b7859c39c4b158fa3932cfbfe1e982022-12-22T02:35:15ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2022-08-011310.3389/fpls.2022.930721930721Gene network downstream plant stress response modulated by peroxisomal H2O2Laura C. Terrón-Camero0M. Ángeles Peláez-Vico1A. Rodríguez-González2Coral del Val3Coral del Val4Luisa M. Sandalio5María C. Romero-Puertas6Department of Biochemistry and Molecular and Cellular Biology of Plants, Estación Experimental del Zaidín (EEZ), Consejo Superior de Investigaciones Científicas (CSIC), Granada, SpainDepartment of Biochemistry and Molecular and Cellular Biology of Plants, Estación Experimental del Zaidín (EEZ), Consejo Superior de Investigaciones Científicas (CSIC), Granada, SpainDepartment of Biochemistry and Molecular and Cellular Biology of Plants, Estación Experimental del Zaidín (EEZ), Consejo Superior de Investigaciones Científicas (CSIC), Granada, SpainDepartment of Artificial Intelligence, University of Granada, Granada, SpainAndalusian Data Science and Computational Intelligence (DaSCI) Research Institute, University of Granada, Granada, SpainDepartment of Biochemistry and Molecular and Cellular Biology of Plants, Estación Experimental del Zaidín (EEZ), Consejo Superior de Investigaciones Científicas (CSIC), Granada, SpainDepartment of Biochemistry and Molecular and Cellular Biology of Plants, Estación Experimental del Zaidín (EEZ), Consejo Superior de Investigaciones Científicas (CSIC), Granada, SpainReactive oxygen species (ROS) act as secondary messengers that can be sensed by specific redox-sensitive proteins responsible for the activation of signal transduction culminating in altered gene expression. The subcellular site, in which modifications in the ROS/oxidation state occur, can also act as a specific cellular redox network signal. The chemical identity of ROS and their subcellular origin is actually a specific imprint on the transcriptome response. In recent years, a number of transcriptomic studies related to altered ROS metabolism in plant peroxisomes have been carried out. In this study, we conducted a meta-analysis of these transcriptomic findings to identify common transcriptional footprints for plant peroxisomal-dependent signaling at early and later time points. These footprints highlight the regulation of various metabolic pathways and gene families, which are also found in plant responses to several abiotic stresses. Major peroxisomal-dependent genes are associated with protein and endoplasmic reticulum (ER) protection at later stages of stress while, at earlier stages, these genes are related to hormone biosynthesis and signaling regulation. Furthermore, in silico analyses allowed us to assign human orthologs to some of the peroxisomal-dependent proteins, which are mainly associated with different cancer pathologies. Peroxisomal footprints provide a valuable resource for assessing and supporting key peroxisomal functions in cellular metabolism under control and stress conditions across species.https://www.frontiersin.org/articles/10.3389/fpls.2022.930721/fullabiotic stressjasmonic acidperoxisomesreactive oxygen speciessignaling |
| spellingShingle | Laura C. Terrón-Camero M. Ángeles Peláez-Vico A. Rodríguez-González Coral del Val Coral del Val Luisa M. Sandalio María C. Romero-Puertas Gene network downstream plant stress response modulated by peroxisomal H2O2 Frontiers in Plant Science abiotic stress jasmonic acid peroxisomes reactive oxygen species signaling |
| title | Gene network downstream plant stress response modulated by peroxisomal H2O2 |
| title_full | Gene network downstream plant stress response modulated by peroxisomal H2O2 |
| title_fullStr | Gene network downstream plant stress response modulated by peroxisomal H2O2 |
| title_full_unstemmed | Gene network downstream plant stress response modulated by peroxisomal H2O2 |
| title_short | Gene network downstream plant stress response modulated by peroxisomal H2O2 |
| title_sort | gene network downstream plant stress response modulated by peroxisomal h2o2 |
| topic | abiotic stress jasmonic acid peroxisomes reactive oxygen species signaling |
| url | https://www.frontiersin.org/articles/10.3389/fpls.2022.930721/full |
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