Characterization of the Dahl salt-sensitive rat as a rodent model of inherited, widespread, persistent pain

Abstract Animal models are essential for studying the pathophysiology of chronic pain disorders and as screening tools for new therapies. However, most models available do not reproduce key characteristics of clinical persistent pain. This has limited their ability to accurately predict which new me...

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Bibliographic Details
Main Authors: Luiz F. Ferrari, Charles Rey, Anna Ramirez, Adam Dziuba, Jacqueline Zickella, Michael Zickella, Hershel Raff, Norman E. Taylor
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24094-9