Immunogenicity and Clinical Efficacy of Influenza Vaccination In Pregnancy
Pregnant women are at high risk from influenza due to disproportionate morbidity, mortality, and adverse pregnancy outcomes following infection. As such, they are classified as a high priority group for vaccination. However, changes in the maternal immune system required to accommodate the allogenei...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2015-06-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00289/full |
| _version_ | 1819072462263943168 |
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| author | Alexander W Kay Catherine A Blish |
| author_facet | Alexander W Kay Catherine A Blish |
| author_sort | Alexander W Kay |
| collection | DOAJ |
| description | Pregnant women are at high risk from influenza due to disproportionate morbidity, mortality, and adverse pregnancy outcomes following infection. As such, they are classified as a high priority group for vaccination. However, changes in the maternal immune system required to accommodate the allogeneic fetus may alter the immunogenicity of influenza vaccines. A large number of studies have evaluated the safety of the influenza vaccine. Here, we will review available studies on the immunogenicity and efficacy of the influenza vaccine during pregnancy, focusing on both humoral and cellular immunity. |
| first_indexed | 2024-12-21T17:38:06Z |
| format | Article |
| id | doaj.art-2c3f4b18443f49e1a494002f4c8cb4b1 |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-12-21T17:38:06Z |
| publishDate | 2015-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-2c3f4b18443f49e1a494002f4c8cb4b12022-12-21T18:55:43ZengFrontiers Media S.A.Frontiers in Immunology1664-32242015-06-01610.3389/fimmu.2015.00289145632Immunogenicity and Clinical Efficacy of Influenza Vaccination In PregnancyAlexander W Kay0Catherine A Blish1Stanford University School of MedicineStanford University School of MedicinePregnant women are at high risk from influenza due to disproportionate morbidity, mortality, and adverse pregnancy outcomes following infection. As such, they are classified as a high priority group for vaccination. However, changes in the maternal immune system required to accommodate the allogeneic fetus may alter the immunogenicity of influenza vaccines. A large number of studies have evaluated the safety of the influenza vaccine. Here, we will review available studies on the immunogenicity and efficacy of the influenza vaccine during pregnancy, focusing on both humoral and cellular immunity.http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00289/fullPregnancyantibodyinfluenzaImmunogenicityInactivated influenza vaccine |
| spellingShingle | Alexander W Kay Catherine A Blish Immunogenicity and Clinical Efficacy of Influenza Vaccination In Pregnancy Frontiers in Immunology Pregnancy antibody influenza Immunogenicity Inactivated influenza vaccine |
| title | Immunogenicity and Clinical Efficacy of Influenza Vaccination In Pregnancy |
| title_full | Immunogenicity and Clinical Efficacy of Influenza Vaccination In Pregnancy |
| title_fullStr | Immunogenicity and Clinical Efficacy of Influenza Vaccination In Pregnancy |
| title_full_unstemmed | Immunogenicity and Clinical Efficacy of Influenza Vaccination In Pregnancy |
| title_short | Immunogenicity and Clinical Efficacy of Influenza Vaccination In Pregnancy |
| title_sort | immunogenicity and clinical efficacy of influenza vaccination in pregnancy |
| topic | Pregnancy antibody influenza Immunogenicity Inactivated influenza vaccine |
| url | http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00289/full |
| work_keys_str_mv | AT alexanderwkay immunogenicityandclinicalefficacyofinfluenzavaccinationinpregnancy AT catherineablish immunogenicityandclinicalefficacyofinfluenzavaccinationinpregnancy |