Quantitative Measurement of The Knee Joint Cartilage Signal Intensity (SI) When T2map Sequence Applied to Define a Biomarker for Early Detection of Osteoarthritis (OA) Based on Bmi Groups
This quantitative study was an experimental design. A total of 18 healthy male and female volunteers, with differnt BMI involved in the study by consecutive random sampling. An expert Radiologist evaluated all the 38 T2map images being studied. The arbitrary SI data were measured using one millimete...
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| Format: | Article |
| Language: | Indonesian |
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UPPM, Poltekkes Kemenkes Semarang
2015-08-01
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| Series: | Jurnal Riset Kesehatan |
| Subjects: | |
| Online Access: | http://ejournal.poltekkes-smg.ac.id/ojs/index.php/jrk/article/view/232 |
| _version_ | 1828893768597635072 |
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| author | Sugiyanto Sugiyanto Gatot Murti Wibowo Heru Trisikwanto |
| author_facet | Sugiyanto Sugiyanto Gatot Murti Wibowo Heru Trisikwanto |
| author_sort | Sugiyanto Sugiyanto |
| collection | DOAJ |
| description | This quantitative study was an experimental design. A total of 18 healthy male and female volunteers, with differnt BMI involved in the study by consecutive random sampling. An expert Radiologist evaluated all the 38 T2map images being studied. The arbitrary SI data were measured using one millimeter ROI of the machine measurement tools and the values of T2map were based on a fitted exponential decay calculation ?generated from the graphs developed by the Window excel. The mean differences amongst T2map values on the sagital plan femoro-tibial cartilage and coronal plan femoro-tibial (medial and lateral) were statistically tested using One-way Anova, and all the T2map images also graded by the radiologist following the OA the grading levels as published Internationally. In conclusion, an increased TE on the application of multi-spin echo sequence T2map, causing the calculated T2map values v? aried not only in the sagital area of t?he knee joint cartilage of the femoral and tibial but also in the coronal femoro-tibial (medial and lateral) for both the male and female healthy volunteer subjects, and different BMI category (under-weight, normal-weight, verweight). The values ?T2map within and between BMI group and among different gender showed statistically no difference (p-value > 0.05). The averaged T2map and its tandard deviations have been used to define t?he T2map biomarkers (baseline T? 2map values) in each BMJ group subjects and between gender for both of the knee joint sagital and coronal planes despite the 1.5T MRI modality is not facilitated to commercial qMRI supporting software. |
| first_indexed | 2024-12-13T14:00:03Z |
| format | Article |
| id | doaj.art-2c40226461c04d0690138b9bce4fdf2d |
| institution | Directory Open Access Journal |
| issn | 2252-5068 2461-1026 |
| language | Indonesian |
| last_indexed | 2024-12-13T14:00:03Z |
| publishDate | 2015-08-01 |
| publisher | UPPM, Poltekkes Kemenkes Semarang |
| record_format | Article |
| series | Jurnal Riset Kesehatan |
| spelling | doaj.art-2c40226461c04d0690138b9bce4fdf2d2022-12-21T23:42:46ZindUPPM, Poltekkes Kemenkes SemarangJurnal Riset Kesehatan2252-50682461-10262015-08-013146747610.31983/jrk.v3i1.232203Quantitative Measurement of The Knee Joint Cartilage Signal Intensity (SI) When T2map Sequence Applied to Define a Biomarker for Early Detection of Osteoarthritis (OA) Based on Bmi GroupsSugiyanto Sugiyanto0Gatot Murti Wibowo1Heru Trisikwanto2Technic of Radiodiagnostic and Radiotherapy Department, Polytechnic Health Ministry of SemarangTechnic of Radiodiagnostic and Radiotherapy Department, Polytechnic Health Ministry of SemarangTechnic of Radiodiagnostic and Radiotherapy Department, Polytechnic Health Ministry of SemarangThis quantitative study was an experimental design. A total of 18 healthy male and female volunteers, with differnt BMI involved in the study by consecutive random sampling. An expert Radiologist evaluated all the 38 T2map images being studied. The arbitrary SI data were measured using one millimeter ROI of the machine measurement tools and the values of T2map were based on a fitted exponential decay calculation ?generated from the graphs developed by the Window excel. The mean differences amongst T2map values on the sagital plan femoro-tibial cartilage and coronal plan femoro-tibial (medial and lateral) were statistically tested using One-way Anova, and all the T2map images also graded by the radiologist following the OA the grading levels as published Internationally. In conclusion, an increased TE on the application of multi-spin echo sequence T2map, causing the calculated T2map values v? aried not only in the sagital area of t?he knee joint cartilage of the femoral and tibial but also in the coronal femoro-tibial (medial and lateral) for both the male and female healthy volunteer subjects, and different BMI category (under-weight, normal-weight, verweight). The values ?T2map within and between BMI group and among different gender showed statistically no difference (p-value > 0.05). The averaged T2map and its tandard deviations have been used to define t?he T2map biomarkers (baseline T? 2map values) in each BMJ group subjects and between gender for both of the knee joint sagital and coronal planes despite the 1.5T MRI modality is not facilitated to commercial qMRI supporting software.http://ejournal.poltekkes-smg.ac.id/ojs/index.php/jrk/article/view/232T2map MRIOAknee joint-cartilageBMI groupgender |
| spellingShingle | Sugiyanto Sugiyanto Gatot Murti Wibowo Heru Trisikwanto Quantitative Measurement of The Knee Joint Cartilage Signal Intensity (SI) When T2map Sequence Applied to Define a Biomarker for Early Detection of Osteoarthritis (OA) Based on Bmi Groups Jurnal Riset Kesehatan T2map MRI OA knee joint-cartilage BMI group gender |
| title | Quantitative Measurement of The Knee Joint Cartilage Signal Intensity (SI) When T2map Sequence Applied to Define a Biomarker for Early Detection of Osteoarthritis (OA) Based on Bmi Groups |
| title_full | Quantitative Measurement of The Knee Joint Cartilage Signal Intensity (SI) When T2map Sequence Applied to Define a Biomarker for Early Detection of Osteoarthritis (OA) Based on Bmi Groups |
| title_fullStr | Quantitative Measurement of The Knee Joint Cartilage Signal Intensity (SI) When T2map Sequence Applied to Define a Biomarker for Early Detection of Osteoarthritis (OA) Based on Bmi Groups |
| title_full_unstemmed | Quantitative Measurement of The Knee Joint Cartilage Signal Intensity (SI) When T2map Sequence Applied to Define a Biomarker for Early Detection of Osteoarthritis (OA) Based on Bmi Groups |
| title_short | Quantitative Measurement of The Knee Joint Cartilage Signal Intensity (SI) When T2map Sequence Applied to Define a Biomarker for Early Detection of Osteoarthritis (OA) Based on Bmi Groups |
| title_sort | quantitative measurement of the knee joint cartilage signal intensity si when t2map sequence applied to define a biomarker for early detection of osteoarthritis oa based on bmi groups |
| topic | T2map MRI OA knee joint-cartilage BMI group gender |
| url | http://ejournal.poltekkes-smg.ac.id/ojs/index.php/jrk/article/view/232 |
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