A novel method for early detection of colorectal cancer based on detection of methylation of two fragments of syndecan-2 (SDC2) in stool DNA

A novel method for early detection of colorectal cancer based on detection of methylation of two fragments of syndecan-2 (SDC2) in stool DNA

Abstract Background Methylated SDC2 has been proved as a diagnostic marker for human colorectal cancer (CRC), noninvasive stool DNA-based methylation testing also emerges as a novel approach for detecting CRC. The aim of this study was to evaluate the clinical performance of stool DNA-based SDC2 met...

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Bibliographic Details
Main Authors: Liang Ma, Geng Qin, Fei Gai, Yongwei Jiang, Zhan Huang, Hui Yang, Shukun Yao, Shiyu Du, Yongtong Cao
Format: Article
Language:English
Published: BMC 2022-04-01
Series:BMC Gastroenterology
Subjects:
Colorectal cancer
Combined detection
Methylation
SDC2
Stool DNA
Online Access:https://doi.org/10.1186/s12876-022-02264-3

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