Multicomponent magnetic spinels: From complexity of crystal chemistry to coupled magnetic resonance imaging (MRI)
Spinels have a rich history that spans complexities of their structures to multitude of useful properties and intriguing phenomena. Herein, we demonstrate the versatility and elegance of ferrite-spinel based magnetic nanostructures (MNSs) as a contrast agent in magnetic resonance imaging (MRI). We s...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
AIP Publishing LLC
2023-05-01
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| Series: | APL Materials |
| Online Access: | http://dx.doi.org/10.1063/5.0141055 |
| _version_ | 1797771748911874048 |
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| author | Vikas Nandwana Vinayak P. Dravid |
| author_facet | Vikas Nandwana Vinayak P. Dravid |
| author_sort | Vikas Nandwana |
| collection | DOAJ |
| description | Spinels have a rich history that spans complexities of their structures to multitude of useful properties and intriguing phenomena. Herein, we demonstrate the versatility and elegance of ferrite-spinel based magnetic nanostructures (MNSs) as a contrast agent in magnetic resonance imaging (MRI). We show that the magnetic properties of the inverse spinel Fe3O4 MNS can be enhanced by tuning their crystal chemistry. After doping with Mn2+ and Zn2+ into Fe3O4 MNS at a right stoichiometry, high saturation magnetization and magnetic anisotropy were observed due to rearrangement and specific positions of Mn2+, Zn2+, Fe2+, and Fe3+ cations in the inverse spinel AB2O4 crystal lattice. The improved magnetic properties were leveraged to develop T1-weighted MRI contrast agent that are more biocompatible and efficient than currently used Gd-based complexes. This work underscores the rich opportunities in magnetic spinels for not only unusual applications as in MRI contrast enhancement but also the complexity and versatility of its crystal chemistry that forms the basis for its diverse properties. |
| first_indexed | 2024-03-12T21:42:06Z |
| format | Article |
| id | doaj.art-2c44c5f1e1794a1a9edd1c98db8e232c |
| institution | Directory Open Access Journal |
| issn | 2166-532X |
| language | English |
| last_indexed | 2024-03-12T21:42:06Z |
| publishDate | 2023-05-01 |
| publisher | AIP Publishing LLC |
| record_format | Article |
| series | APL Materials |
| spelling | doaj.art-2c44c5f1e1794a1a9edd1c98db8e232c2023-07-26T15:44:37ZengAIP Publishing LLCAPL Materials2166-532X2023-05-01115050701050701-810.1063/5.0141055Multicomponent magnetic spinels: From complexity of crystal chemistry to coupled magnetic resonance imaging (MRI)Vikas Nandwana0Vinayak P. Dravid1Department of Materials Science & Engineering, Northwestern University, Evanston, Illinois 60208, USADepartment of Materials Science & Engineering, Northwestern University, Evanston, Illinois 60208, USASpinels have a rich history that spans complexities of their structures to multitude of useful properties and intriguing phenomena. Herein, we demonstrate the versatility and elegance of ferrite-spinel based magnetic nanostructures (MNSs) as a contrast agent in magnetic resonance imaging (MRI). We show that the magnetic properties of the inverse spinel Fe3O4 MNS can be enhanced by tuning their crystal chemistry. After doping with Mn2+ and Zn2+ into Fe3O4 MNS at a right stoichiometry, high saturation magnetization and magnetic anisotropy were observed due to rearrangement and specific positions of Mn2+, Zn2+, Fe2+, and Fe3+ cations in the inverse spinel AB2O4 crystal lattice. The improved magnetic properties were leveraged to develop T1-weighted MRI contrast agent that are more biocompatible and efficient than currently used Gd-based complexes. This work underscores the rich opportunities in magnetic spinels for not only unusual applications as in MRI contrast enhancement but also the complexity and versatility of its crystal chemistry that forms the basis for its diverse properties.http://dx.doi.org/10.1063/5.0141055 |
| spellingShingle | Vikas Nandwana Vinayak P. Dravid Multicomponent magnetic spinels: From complexity of crystal chemistry to coupled magnetic resonance imaging (MRI) APL Materials |
| title | Multicomponent magnetic spinels: From complexity of crystal chemistry to coupled magnetic resonance imaging (MRI) |
| title_full | Multicomponent magnetic spinels: From complexity of crystal chemistry to coupled magnetic resonance imaging (MRI) |
| title_fullStr | Multicomponent magnetic spinels: From complexity of crystal chemistry to coupled magnetic resonance imaging (MRI) |
| title_full_unstemmed | Multicomponent magnetic spinels: From complexity of crystal chemistry to coupled magnetic resonance imaging (MRI) |
| title_short | Multicomponent magnetic spinels: From complexity of crystal chemistry to coupled magnetic resonance imaging (MRI) |
| title_sort | multicomponent magnetic spinels from complexity of crystal chemistry to coupled magnetic resonance imaging mri |
| url | http://dx.doi.org/10.1063/5.0141055 |
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