Supramolecular Chromatographic Separation of C<sub>60</sub> and C<sub>70</sub> Fullerenes: Flash Column Chromatography vs. High Pressure Liquid Chromatography
A silica-bound <i>C</i>-butylpyrogallol[4]arene chromatographic stationary phase was prepared and characterised by thermogravimetric analysis, scanning electron microscopy, NMR and mass spectrometry. The chromatographic performance was investigated by using C<sub>60</sub> and...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-05-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/22/11/5726 |
| Summary: | A silica-bound <i>C</i>-butylpyrogallol[4]arene chromatographic stationary phase was prepared and characterised by thermogravimetric analysis, scanning electron microscopy, NMR and mass spectrometry. The chromatographic performance was investigated by using C<sub>60</sub> and C<sub>70</sub> fullerenes in reverse phase mode via flash column and high-pressure liquid chromatography (HPLC). The resulting new stationary phase was observed to demonstrate size-selective molecular recognition as postulated from our in-silico studies. The silica-bound <i>C</i>-butylpyrogallol[4]arene flash and HPLC stationary phases were able to separate a C<sub>60</sub>- and C<sub>70</sub>-fullerene mixture more effectively than an RP-C<sub>18</sub> stationary phase. The presence of toluene in the mobile phase plays a significant role in achieving symmetrical peaks in flash column chromatography. |
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| ISSN: | 1661-6596 1422-0067 |