Transient neonatal myasthenia gravis: case report
Transient neonatal myasthenia gravis (TNMG) is a distinct type of myasthenia gravis (MG), a temporary autoimmune condition due to the mother’s antibodies crossing over the placenta and affecting the baby. Studies suggest that 10 to 15% of infants born to mothers suffering from MG will develop TNMG....
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Amaltea Medical Publishing House
2022-12-01
|
| Series: | Romanian Medical Journal |
| Subjects: | |
| Online Access: | https://rmj.com.ro/articles/2022.4/RMJ_2022_4_Art-03.pdf |
| _version_ | 1797328898660237312 |
|---|---|
| author | Diana Iulia Vasilescu Adriana Mihaela Dan Vlad Dima Monica Mihaela Cirstoiu |
| author_facet | Diana Iulia Vasilescu Adriana Mihaela Dan Vlad Dima Monica Mihaela Cirstoiu |
| author_sort | Diana Iulia Vasilescu |
| collection | DOAJ |
| description | Transient neonatal myasthenia gravis (TNMG) is a distinct type of myasthenia gravis (MG), a temporary autoimmune condition due to the mother’s antibodies crossing over the placenta and affecting the baby. Studies suggest that 10 to 15% of infants born to mothers suffering from MG will develop TNMG. Undoubtedly, if not diagnosed and treated in time, TNMG can be a serious condition, even life-threatening. Almost 80% of newborns will present symptoms in the first 24 hours of life that will last up to 4 weeks and a complete recovery is expected by 2 months of age. Only 10% of the affected infants may still be symptomatic at 4 months. |
| first_indexed | 2024-03-08T06:58:36Z |
| format | Article |
| id | doaj.art-2c52499d2a824f83a4939a4b989a94d0 |
| institution | Directory Open Access Journal |
| issn | 1220-5478 2069-606X |
| language | English |
| last_indexed | 2024-03-08T06:58:36Z |
| publishDate | 2022-12-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Medical Journal |
| spelling | doaj.art-2c52499d2a824f83a4939a4b989a94d02024-02-03T06:23:27ZengAmaltea Medical Publishing HouseRomanian Medical Journal1220-54782069-606X2022-12-0169416616810.37897/RMJ.2022.4.3Transient neonatal myasthenia gravis: case report Diana Iulia Vasilescu0Adriana Mihaela Dan1Vlad Dima2Monica Mihaela Cirstoiu3Doctoral School, ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; Department of Neonatology, Emergency University Hospital Bucharest, RomaniaDepartment of Neonatology, Emergency University Hospital Bucharest, RomaniaFilantropia Clinical Hospital, Bucharest, Romania”Carol Davila” University of Medicine and Pharmacy Bucharest, Romania; Department of Obstetrics and Gynecology, Emergency University Hospital Bucharest, RomaniaTransient neonatal myasthenia gravis (TNMG) is a distinct type of myasthenia gravis (MG), a temporary autoimmune condition due to the mother’s antibodies crossing over the placenta and affecting the baby. Studies suggest that 10 to 15% of infants born to mothers suffering from MG will develop TNMG. Undoubtedly, if not diagnosed and treated in time, TNMG can be a serious condition, even life-threatening. Almost 80% of newborns will present symptoms in the first 24 hours of life that will last up to 4 weeks and a complete recovery is expected by 2 months of age. Only 10% of the affected infants may still be symptomatic at 4 months.https://rmj.com.ro/articles/2022.4/RMJ_2022_4_Art-03.pdfmyasthenia gravisacetylcholine receptorantibodieshypotonianeostigmine |
| spellingShingle | Diana Iulia Vasilescu Adriana Mihaela Dan Vlad Dima Monica Mihaela Cirstoiu Transient neonatal myasthenia gravis: case report Romanian Medical Journal myasthenia gravis acetylcholine receptor antibodies hypotonia neostigmine |
| title | Transient neonatal myasthenia gravis: case report |
| title_full | Transient neonatal myasthenia gravis: case report |
| title_fullStr | Transient neonatal myasthenia gravis: case report |
| title_full_unstemmed | Transient neonatal myasthenia gravis: case report |
| title_short | Transient neonatal myasthenia gravis: case report |
| title_sort | transient neonatal myasthenia gravis case report |
| topic | myasthenia gravis acetylcholine receptor antibodies hypotonia neostigmine |
| url | https://rmj.com.ro/articles/2022.4/RMJ_2022_4_Art-03.pdf |
| work_keys_str_mv | AT dianaiuliavasilescu transientneonatalmyastheniagraviscasereport AT adrianamihaeladan transientneonatalmyastheniagraviscasereport AT vladdima transientneonatalmyastheniagraviscasereport AT monicamihaelacirstoiu transientneonatalmyastheniagraviscasereport |