Real-Time Determination of Intracellular cAMP Reveals Functional Coupling of G<sub>s</sub> Protein to the Melatonin MT<sub>1</sub> Receptor

Real-Time Determination of Intracellular cAMP Reveals Functional Coupling of G<sub>s</sub> Protein to the Melatonin MT<sub>1</sub> Receptor

Melatonin is a neuroendocrine hormone that regulates the circadian rhythm and many other physiological processes. Its functions are primarily exerted through two subtypes of human melatonin receptors, termed melatonin type-1 (MT<sub>1</sub>) and type-2 (MT<sub>2</sub>) recept...

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Bibliographic Details
Main Authors: Lap Hang Tse, Suet Ting Cheung, Seayoung Lee, Yung Hou Wong
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
adenylyl cyclase
G protein
melatonin receptor
modeling
Online Access:https://www.mdpi.com/1422-0067/25/5/2919

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