The Effect of Platelet-Rich Fibrin on Postoperative Morbidity after Rhinoplasty: A Comparative Analysis with Respect to Edema, Ecchymosis and Pain

Aim:Platelet-rich fibrin (PRF) effectively improves the surgical effect in augmentation rhinoplasty; while there are a limited number of studies regarding its impact on postoperative morbidity in primary open rhinoplasty with conventional osteotomy (COS). This study was designed to investigate the u...

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Main Authors: Enes Yigit, Tolga Kirgezen, Ozan Ozdemir, Muhammet Ture, Abdurrahman Cagliyan, Ozgur Yigit
Format: Article
Language:English
Published: Galenos Yayinevi 2022-06-01
Series:Haseki Tıp Bülteni
Subjects:
Online Access: http://www.hasekidergisi.com/archives/archive-detail/article-preview/the-effect-of-platelet-rich-fibrin-on-postoperativ/52223
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author Enes Yigit
Tolga Kirgezen
Ozan Ozdemir
Muhammet Ture
Abdurrahman Cagliyan
Ozgur Yigit
author_facet Enes Yigit
Tolga Kirgezen
Ozan Ozdemir
Muhammet Ture
Abdurrahman Cagliyan
Ozgur Yigit
author_sort Enes Yigit
collection DOAJ
description Aim:Platelet-rich fibrin (PRF) effectively improves the surgical effect in augmentation rhinoplasty; while there are a limited number of studies regarding its impact on postoperative morbidity in primary open rhinoplasty with conventional osteotomy (COS). This study was designed to investigate the utility of PRF in reducing the short-term postoperative morbidity in primary open rhinoplasty with conventional osteotomy.Methods:A total of 61 adult patients who underwent primary open rhinoplasty with conventional osteotomy, either alone (COS group; n=31) or combined with the application of PRF over the osteotomy line (COS-PRF group; n=30) were included in this prospective study conducted between March 1, 2020 and March 1, 2021. Data on postoperative morbidity, including edema and periorbital ecchymosis (on postoperative day 2 and day 7), pain [via visual analogue scale (VAS) and verbal rating scale (VRS)] and the analgesic use (on postoperative days 1, 2, 3 and 7) were recorded.Results:COS and COS-PRF groups were similar in terms of the likelihood of eyelid edema and periorbital ecchymosis on any postoperative day. The study groups were also similar in terms of average VAS (median 2.5 vs. 2.4, p=0.680) and VRS (median 1.5 vs. 1.4, p=0.521) scores and the number of analgesics used (median 1.5 vs. 1.3, p=0.196) during the 7-day postoperative period and daily VAS, VRS and analgesic usage records.Conclusion:Our findings indicate no significant impact of using local PRF application over osteotomy line in reducing postoperative eyelid edema, periorbital ecchymosis, or pain within the first postoperative week of open rhinoplasty.
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spelling doaj.art-2c5bc3d054f14d458883cdcf44f208e72023-02-15T16:13:56ZengGalenos YayineviHaseki Tıp Bülteni1302-00722147-26882022-06-0160324024710.4274/haseki.galenos.2022.808413049054The Effect of Platelet-Rich Fibrin on Postoperative Morbidity after Rhinoplasty: A Comparative Analysis with Respect to Edema, Ecchymosis and PainEnes Yigit0Tolga Kirgezen1Ozan Ozdemir2Muhammet Ture3Abdurrahman Cagliyan4Ozgur Yigit5 University of Health Sciences Turkey, Istanbul Training and Research Hospital, Clinic of Otorhinolaryngology, Istanbul, Turkey University of Health Sciences Turkey, Istanbul Training and Research Hospital, Clinic of Otorhinolaryngology, Istanbul, Turkey University of Health Sciences Turkey, Istanbul Training and Research Hospital, Clinic of Otorhinolaryngology, Istanbul, Turkey University of Health Sciences Turkey, Istanbul Training and Research Hospital, Clinic of Otorhinolaryngology, Istanbul, Turkey University of Health Sciences Turkey, Istanbul Training and Research Hospital, Clinic of Otorhinolaryngology, Istanbul, Turkey University of Health Sciences Turkey, Istanbul Training and Research Hospital, Clinic of Otorhinolaryngology, Istanbul, Turkey Aim:Platelet-rich fibrin (PRF) effectively improves the surgical effect in augmentation rhinoplasty; while there are a limited number of studies regarding its impact on postoperative morbidity in primary open rhinoplasty with conventional osteotomy (COS). This study was designed to investigate the utility of PRF in reducing the short-term postoperative morbidity in primary open rhinoplasty with conventional osteotomy.Methods:A total of 61 adult patients who underwent primary open rhinoplasty with conventional osteotomy, either alone (COS group; n=31) or combined with the application of PRF over the osteotomy line (COS-PRF group; n=30) were included in this prospective study conducted between March 1, 2020 and March 1, 2021. Data on postoperative morbidity, including edema and periorbital ecchymosis (on postoperative day 2 and day 7), pain [via visual analogue scale (VAS) and verbal rating scale (VRS)] and the analgesic use (on postoperative days 1, 2, 3 and 7) were recorded.Results:COS and COS-PRF groups were similar in terms of the likelihood of eyelid edema and periorbital ecchymosis on any postoperative day. The study groups were also similar in terms of average VAS (median 2.5 vs. 2.4, p=0.680) and VRS (median 1.5 vs. 1.4, p=0.521) scores and the number of analgesics used (median 1.5 vs. 1.3, p=0.196) during the 7-day postoperative period and daily VAS, VRS and analgesic usage records.Conclusion:Our findings indicate no significant impact of using local PRF application over osteotomy line in reducing postoperative eyelid edema, periorbital ecchymosis, or pain within the first postoperative week of open rhinoplasty. http://www.hasekidergisi.com/archives/archive-detail/article-preview/the-effect-of-platelet-rich-fibrin-on-postoperativ/52223 platelet-rich fibrinrhinoplastyosteotomymorbidity
spellingShingle Enes Yigit
Tolga Kirgezen
Ozan Ozdemir
Muhammet Ture
Abdurrahman Cagliyan
Ozgur Yigit
The Effect of Platelet-Rich Fibrin on Postoperative Morbidity after Rhinoplasty: A Comparative Analysis with Respect to Edema, Ecchymosis and Pain
Haseki Tıp Bülteni
platelet-rich fibrin
rhinoplasty
osteotomy
morbidity
title The Effect of Platelet-Rich Fibrin on Postoperative Morbidity after Rhinoplasty: A Comparative Analysis with Respect to Edema, Ecchymosis and Pain
title_full The Effect of Platelet-Rich Fibrin on Postoperative Morbidity after Rhinoplasty: A Comparative Analysis with Respect to Edema, Ecchymosis and Pain
title_fullStr The Effect of Platelet-Rich Fibrin on Postoperative Morbidity after Rhinoplasty: A Comparative Analysis with Respect to Edema, Ecchymosis and Pain
title_full_unstemmed The Effect of Platelet-Rich Fibrin on Postoperative Morbidity after Rhinoplasty: A Comparative Analysis with Respect to Edema, Ecchymosis and Pain
title_short The Effect of Platelet-Rich Fibrin on Postoperative Morbidity after Rhinoplasty: A Comparative Analysis with Respect to Edema, Ecchymosis and Pain
title_sort effect of platelet rich fibrin on postoperative morbidity after rhinoplasty a comparative analysis with respect to edema ecchymosis and pain
topic platelet-rich fibrin
rhinoplasty
osteotomy
morbidity
url http://www.hasekidergisi.com/archives/archive-detail/article-preview/the-effect-of-platelet-rich-fibrin-on-postoperativ/52223
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