Adiposomes from Obese-Diabetic Individuals Promote Endothelial Dysfunction and Loss of Surface Caveolae

Adiposomes from Obese-Diabetic Individuals Promote Endothelial Dysfunction and Loss of Surface Caveolae

Glycosphingolipids (GSLs) are products of lipid glycosylation that have been implicated in the development of cardiovascular diseases. In diabetes, the adipocyte microenvironment is characterized by hyperglycemia and inflammation, resulting in high levels of GSLs. Therefore, we sought to assess the...

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Bibliographic Details
Main Authors: Imaduddin Mirza, Mohamed Haloul, Chandra Hassan, Mario Masrur, Amro Mostafa, Francesco M. Bianco, Mohamed M. Ali, Richard D. Minshall, Abeer M. Mahmoud
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cells
Subjects:
extracellular vesicles
adiposomes
glycosphingolipids (GSLs)
endothelial dysfunction
caveolae
Src kinase
Online Access:https://www.mdpi.com/2073-4409/12/20/2453

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