PD-L1 diagnostic tests: a systematic literature review of scoring algorithms and test-validation metrics

PD-L1 diagnostic tests: a systematic literature review of scoring algorithms and test-validation metrics

Abstract Background The programmed death receptor 1 (PD-1) protein is a cell-surface receptor on certain lymphocytes that, with its ligand programmed death ligand 1 (PD-L1), helps to down-regulate immune responses. Many cancer types express PD-L1 and evade immune recognition via the PD-1/PD-L1 inter...

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Bibliographic Details
Main Authors: Margarita Udall, Maria Rizzo, Juliet Kenny, Jim Doherty, SueAnn Dahm, Paul Robbins, Eric Faulkner
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Diagnostic Pathology
Subjects:
Cancer
Immunotherapy
Programmed death ligand 1
Programmed cell death protein 1
PD-1
PD-L1
Online Access:http://link.springer.com/article/10.1186/s13000-018-0689-9

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