Hypercapnic hyperventilation shortens emergence time from Propofol and Isoflurane anesthesia
Objective: The aim of this study is to compare the effects of hypercapnic hyperventilation and normocapnic normoventilation on emergence time from propofol and isoflurane anesthesia. Methods: In this clinical trial, the differences in emergence time were evaluated in 80 patients undergoing elective...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2013-01-01
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| Series: | Journal of Research in Pharmacy Practice |
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| Online Access: | http://www.jrpp.net/article.asp?issn=2319-9644;year=2013;volume=2;issue=1;spage=24;epage=28;aulast=Yaraghi |
| _version_ | 1811215760942432256 |
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| author | Ahmad Yaraghi Mohammad Golparvar Reihanak Talakoub Hossein Sateie Ali Mehrabi |
| author_facet | Ahmad Yaraghi Mohammad Golparvar Reihanak Talakoub Hossein Sateie Ali Mehrabi |
| author_sort | Ahmad Yaraghi |
| collection | DOAJ |
| description | Objective: The aim of this study is to compare the effects of hypercapnic hyperventilation and normocapnic normoventilation on emergence time from propofol and isoflurane anesthesia.
Methods: In this clinical trial, the differences in emergence time were evaluated in 80 patients undergoing elective abdominal surgery in Alzahra University hospital, Isfahan, Iran, in 2011-2012. Patients were randomly divided into four groups (groups 1-4) receiving isoflurane hypercapnic hyperventilation, isoflurane normocapnic normoventilation, propofol hypercapnic hyperventilation, and propofol normocapnic normoventilation, respectively. Hypercapnia was maintained by adding CO 2 to the patient′s inspired gas during hyperventilation. The emergence time and the duration of stay in recovery room in the four groups were measured and compared by one-way analysis of variance (ANOVA) and least significant difference tests.
Findings: The average emergence time in groups 1, 2, 3, and 4 were (11.3 ± 3.2), (15.2 ± 3.8), (9 ± 4.2) and (11.8 ± 5.3) min, respectively. These differences were significant ( P = 0.001). In patients receiving propofol hypercapnic hyperventilation, the emergence time was faster than in other groups. There was also a significant difference in duration of stay in recovery room between the groups ( P = 0.004). Patients who received isoflurane hypercapnic hyperventilation had a shortest length of stay in the recovery room.
Conclusion: The emergence time after intravenous anesthesia with propofol can be shortened significantly by using hyperventilation and hypercapnia, without any side effects. |
| first_indexed | 2024-04-12T06:27:51Z |
| format | Article |
| id | doaj.art-2c5e745676cc46e0aa840a02cfae16ff |
| institution | Directory Open Access Journal |
| issn | 2319-9644 2279-042X |
| language | English |
| last_indexed | 2024-04-12T06:27:51Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Research in Pharmacy Practice |
| spelling | doaj.art-2c5e745676cc46e0aa840a02cfae16ff2022-12-22T03:44:06ZengWolters Kluwer Medknow PublicationsJournal of Research in Pharmacy Practice2319-96442279-042X2013-01-0121242810.4103/2279-042X.114085Hypercapnic hyperventilation shortens emergence time from Propofol and Isoflurane anesthesiaAhmad YaraghiMohammad GolparvarReihanak TalakoubHossein SateieAli MehrabiObjective: The aim of this study is to compare the effects of hypercapnic hyperventilation and normocapnic normoventilation on emergence time from propofol and isoflurane anesthesia. Methods: In this clinical trial, the differences in emergence time were evaluated in 80 patients undergoing elective abdominal surgery in Alzahra University hospital, Isfahan, Iran, in 2011-2012. Patients were randomly divided into four groups (groups 1-4) receiving isoflurane hypercapnic hyperventilation, isoflurane normocapnic normoventilation, propofol hypercapnic hyperventilation, and propofol normocapnic normoventilation, respectively. Hypercapnia was maintained by adding CO 2 to the patient′s inspired gas during hyperventilation. The emergence time and the duration of stay in recovery room in the four groups were measured and compared by one-way analysis of variance (ANOVA) and least significant difference tests. Findings: The average emergence time in groups 1, 2, 3, and 4 were (11.3 ± 3.2), (15.2 ± 3.8), (9 ± 4.2) and (11.8 ± 5.3) min, respectively. These differences were significant ( P = 0.001). In patients receiving propofol hypercapnic hyperventilation, the emergence time was faster than in other groups. There was also a significant difference in duration of stay in recovery room between the groups ( P = 0.004). Patients who received isoflurane hypercapnic hyperventilation had a shortest length of stay in the recovery room. Conclusion: The emergence time after intravenous anesthesia with propofol can be shortened significantly by using hyperventilation and hypercapnia, without any side effects.http://www.jrpp.net/article.asp?issn=2319-9644;year=2013;volume=2;issue=1;spage=24;epage=28;aulast=YaraghiEmergence; hypercapnia; hyperventilation; isoflurane; propofol |
| spellingShingle | Ahmad Yaraghi Mohammad Golparvar Reihanak Talakoub Hossein Sateie Ali Mehrabi Hypercapnic hyperventilation shortens emergence time from Propofol and Isoflurane anesthesia Journal of Research in Pharmacy Practice Emergence; hypercapnia; hyperventilation; isoflurane; propofol |
| title | Hypercapnic hyperventilation shortens emergence time from Propofol and Isoflurane anesthesia |
| title_full | Hypercapnic hyperventilation shortens emergence time from Propofol and Isoflurane anesthesia |
| title_fullStr | Hypercapnic hyperventilation shortens emergence time from Propofol and Isoflurane anesthesia |
| title_full_unstemmed | Hypercapnic hyperventilation shortens emergence time from Propofol and Isoflurane anesthesia |
| title_short | Hypercapnic hyperventilation shortens emergence time from Propofol and Isoflurane anesthesia |
| title_sort | hypercapnic hyperventilation shortens emergence time from propofol and isoflurane anesthesia |
| topic | Emergence; hypercapnia; hyperventilation; isoflurane; propofol |
| url | http://www.jrpp.net/article.asp?issn=2319-9644;year=2013;volume=2;issue=1;spage=24;epage=28;aulast=Yaraghi |
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