High-fat diet aggravates postoperative cognitive dysfunction in aged mice

High-fat diet aggravates postoperative cognitive dysfunction in aged mice

Abstract Background Silent Information Regulator 1 (Sirt1) and apoptosis play key roles in postoperative cognitive dysfunction (POCD). Consuming a high-fat diet (HFD), a prevalent type of diet in modern society, has been increasingly recognized as contributing to neurodegenerative diseases. Although...

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Bibliographic Details
Main Authors: Lan Wei, Minmin Yao, Zhimeng Zhao, Hui Jiang, Shengjin Ge
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Anesthesiology
Subjects:
High-fat diet
Postoperative cognitive dysfunction
Sirt1
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12871-018-0482-z

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