The protective effects of polysaccharide extract from Xin-Ji-Er-Kang formula on Ang II-induced HUVECs injury, L-NAME-induced hypertension and cardiovascular remodeling in mice

The protective effects of polysaccharide extract from Xin-Ji-Er-Kang formula on Ang II-induced HUVECs injury, L-NAME-induced hypertension and cardiovascular remodeling in mice

Abstract Background Xin-Ji-Er-Kang (XJEK) is a Chinese herbal formula, which has been reported to exert effective protection against cardiovascular diseases, including hypertension and myocarditis. Methods Cultured human umbilical vascular endothelial cells (HUVECs) were treated with angiotensin II...

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Bibliographic Details
Main Authors: Ling Ding, Pan Cheng, Li Wang, Juan Hu, Yong-xue Zhang, Guo-wei Cai, Guang-yao Huang, Shan Gao
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Hypertension
Cardiac remodeling
Endothelial dysfunction
Oxidative stress
Inflammation
Online Access:http://link.springer.com/article/10.1186/s12906-019-2539-z

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