HIF-1alpha and HIF-2alpha are differentially activated in distinct cell populations in retinal ischaemia.

HIF-1alpha and HIF-2alpha are differentially activated in distinct cell populations in retinal ischaemia.

Hypoxia plays a key role in ischaemic and neovascular disorders of the retina. Cellular responses to oxygen are mediated by hypoxia-inducible transcription factors (HIFs) that are stabilised in hypoxia and induce the expression of a diverse range of genes. The purpose of this study was to define the...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Freya M Mowat, Ulrich F O Luhmann, Alexander J Smith, Clemens Lange, Yanai Duran, Sarah Harten, Deepa Shukla, Patrick H Maxwell, Robin R Ali, James W B Bainbridge
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: Public Library of Science (PLoS) 2010-06-01
Sarja:PLoS ONE
Linkit:http://europepmc.org/articles/PMC2885428?pdf=render

Internet

http://europepmc.org/articles/PMC2885428?pdf=render

Samankaltaisia teoksia