Shiga Toxin 2a Binds to Complement Components C3b and C5 and Upregulates Their Gene Expression in Human Cell Lines
Enterohemorrhagic <i>Escherichia coli</i> (EHEC) infections can cause EHEC-associated hemolytic uremic syndrome (eHUS) via its main virulent factor, Shiga toxins (Stxs). Complement has been reported to be involved in the progression of eHUS. The aim of this study was to investigate the i...
Main Authors: | Sára Kellnerová, Sneha Chatterjee, Rafael Bayarri-Olmos, Louise Justesen, Heribert Talasz, Wilfried Posch, Samyr Kenno, Peter Garred, Dorothea Orth-Höller, Marco Grasse, Reinhard Würzner |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-12-01
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Series: | Toxins |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6651/13/1/8 |
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