Bivalent single domain antibody constructs for effective neutralization of Venezuelan equine encephalitis

Abstract Venezuelan equine encephalitis virus (VEEV) is a mosquito borne alphavirus which leads to high viremia in equines followed by lethal encephalitis and lateral spread to humans. In addition to naturally occurring outbreaks, VEEV is a potential biothreat agent with no approved human vaccine or...

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Bibliographic Details
Main Authors: Jinny L. Liu, Dan Zabetakis, Christina L. Gardner, Crystal W. Burke, Pamela J. Glass, Emily M. Webb, Lisa C. Shriver-Lake, George P. Anderson, James Weger-Lucarelli, Ellen R. Goldman
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-04434-x