Cerebrospinal Fluid IgM and Oligoclonal IgG Bands in Multiple Sclerosis: A Meta-Analysis of Prevalence and Prognosis

Cerebrospinal Fluid IgM and Oligoclonal IgG Bands in Multiple Sclerosis: A Meta-Analysis of Prevalence and Prognosis

The presence of intrathecal IgM synthesis (ITMS) has been associated with an aggressive multiple sclerosis (MS) clinical course. In the present systematic review, we aimed at assessing the prevalence of ITMS among different MS phenotypes. Moreover, we aimed at quantifying the risk of a second relaps...

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Bibliographic Details
Main Authors: Mattia Fonderico, Emilio Portaccio, Lorenzo Razzolini, Luisa Pastò, Angelo Bellinvia, Ilaria Addazio, Matteo Betti, Maria Grazia Aprea, Clara Ballerini, Tiziana Biagioli, Maria Pia Amato
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Brain Sciences
Subjects:
multiple sclerosis
biomarker
intrathecal IgM synthesis
oligoclonal bands
Online Access:https://www.mdpi.com/2076-3425/11/11/1444

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