FOXO1 Is Present in Stomach Epithelium and Determines Gastric Cell Distribution

FOXO1 Is Present in Stomach Epithelium and Determines Gastric Cell Distribution

Background and Aims: Stomach cells can be converted to insulin-producing cells by Neurog3, MafA, and Pdx1 overexpression. Enteroendocrine cells can be similarly made to produce insulin by the deletion of FOXO1. Characteristics and functional properties of FOXO1-expressing stomach cells are not known...

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Bibliographic Details
Main Authors: Wendy M. McKimpson, Taiyi Kuo, Takumi Kitamoto, Sei Higuchi, Jason C. Mills, Rebecca A. Haeusler, Domenico Accili
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Gastro Hep Advances
Subjects:
Enteroendocrine Cells
Diabetes Treatment
Cell Cycle
Parietal Cells
Transcription Factor
Online Access:http://www.sciencedirect.com/science/article/pii/S2772572322000838

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